105202-44-6Relevant articles and documents
Pd(II)-catalyzed regioselective direct arylation of uracil via oxidative Heck reaction using arylboronic acids
Mondal, Biplab,Hazra, Somjit,Roy
supporting information, p. 1077 - 1081 (2015/02/19)
A palladium catalyzed regioselective synthesis of 6-aryl uracils via oxidative Heck reaction (C-H bond functionalization) of uracils and arylboronic acids is reported. The method is simple, atom-economical, and high yielding.
Regioselective arylation of uracil and 4-pyridone derivatives via copper(I) bromide mediated C-H bond activation
Cheng, Chien,Shih, Yu-Chiao,Chen, Hui-Ting,Chien, Tun-Cheng
, p. 1387 - 1396 (2013/02/23)
A facile and effective synthesis of 6-aryluracil derivatives was accomplished by the direct C-H bond activation for arylation. A series of 6-aryl-1,3-dimethyluracils were synthesized from the reaction of 1,3-dimethyluracil with various phenyl iodides in DMF, in the presence of copper(I) bromide as the catalyst and lithium tert-butoxide as the base. This methodology is applicable to a variety of 5-substituted uracils as well as 4-pyridone to provide direct accesses to versatile uracil and 4-pyridone derivatives.
Synthesis of cyclooctapyrimidine-2,4-diones by photocycloaddition of 6-chloro-1,3-dimethyluracil to benzenes in the presence of trifluoroacetic acid
Ohkura,Kanazashi,Seki
, p. 239 - 243 (2007/10/02)
Photoreaction of 6-chloro-1,3-dimethyluracil in benzene and monosubstituted benzenes furnished cycloaddition products, cyclooctapyrimidine-2,4-dione derivatives, in the presence of trifluoroacetic acid.
