1052210-00-0 Usage
Description
(5R)-5-(phenylMethyl)-3-Morpholinone, commonly known as PMPM, is a morpholine derivative with a molecular formula of C12H15NO2. It features a phenylmethyl group attached to the carbon at position 5, which gives it its (5R) configuration. PMPM is a chiral compound that is widely utilized as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its potential biological activities, such as inhibiting acetylcholinesterase, make it a significant molecule in medicinal chemistry and drug discovery.
Uses
Used in Pharmaceutical Synthesis:
(5R)-5-(phenylMethyl)-3-Morpholinone is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and chiral center allow for the development of new and effective medications.
Used in Agrochemical Synthesis:
In the agrochemical industry, PMPM is used as an intermediate in the production of various agrochemicals, such as pesticides and herbicides. Its versatility in chemical reactions contributes to the development of innovative and efficient products for agricultural use.
Used in Medicinal Chemistry Research:
(5R)-5-(phenylMethyl)-3-Morpholinone is used as a pharmacologically active molecule in medicinal chemistry research. Its potential biological activities, including its role as an inhibitor of acetylcholinesterase, make it a promising candidate for the development of new therapeutic agents.
Used in Drug Discovery:
PMPM is utilized in drug discovery efforts due to its potential as a pharmacologically active molecule. Its unique structure and chiral center provide opportunities for the development of novel drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1052210-00-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,2,2,1 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1052210-00:
(9*1)+(8*0)+(7*5)+(6*2)+(5*2)+(4*1)+(3*0)+(2*0)+(1*0)=70
70 % 10 = 0
So 1052210-00-0 is a valid CAS Registry Number.
1052210-00-0Relevant articles and documents
4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase
Alexander, Rikki,Balasundaram, Ahrani,Batchelor, Mark,Brookings, Daniel,Crepy, Karen,Crabbe, Tom,Deltent, Marie-France,Driessens, Frank,Gill, Andrew,Harris, Sue,Hutchinson, Gillian,Kulisa, Claire,Merriman, Mark,Mistry, Prakash,Parton, Ted,Turner, James,Whitcombe, Ian,Wright, Sara
scheme or table, p. 4316 - 4320 (2009/04/06)
4-(1,3-Thiazol-2-yl)morpholine derivatives have been identified as potent and selective inhibitors of phosphoinositide 3-kinase. The SAR data of selected examples are presented and the in vivo profiling of compound 18 is shown to demonstrate the utility of this class of compounds in xenograft models of tumor growth.