1053190-27-4

Basic information

• Product Name: N-{2-[3,3-dimethoxy-2-(4-methoxyphenyl)propionyl]-5-methoxyphenyl}acetamide
• Synonyms: N-{2-[3,3-dimethoxy-2-(4-methoxyphenyl)propionyl]-5-methoxyphenyl}acetamide
• CAS NO: 1053190-27-4
• Molecular Weight: 387.433
• Mol File: 1053190-27-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-{2-[3,3-dimethoxy-2-(4-methoxyphenyl)propionyl]-5-methoxyphenyl}acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2-[3,3-dimethoxy-2-(4-methoxyphenyl)propionyl]-5-methoxyphenyl}acetamide(1053190-27-4)
• EPA Substance Registry System: N-{2-[3,3-dimethoxy-2-(4-methoxyphenyl)propionyl]-5-methoxyphenyl}acetamide(1053190-27-4)

Safety Data

• Hazardous Substances Data: 1053190-27-4(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 42465-53-2 1-(2-amino-4-methoxyphenyl)ethanone 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 286410-78-4 7-methoxy-3-(4-methoxyphenyl)-1H-quinolin-4-one 
• 1621002-96-7 7-hydroxy-3-(4-hydroxyphenyl)-1-benzyl-1H-quinolin-4-one 
• 327593-70-4 7-methoxy-3-(4-methoxyphenyl)-1-methyl-1H-quinolin-4-one 
• 1228466-41-8 7-methoxy-3-(4-methoxy-phenyl)-1-ethyl-1H-quinolin-4-one 
• 1621002-86-5 7-methoxy-3-(4-methoxyphenyl)-1-propyl-1H-quinolin-4-one 
• 1621002-87-6 7-methoxy-3-(4-methoxyphenyl)-1-(3-methylbutyl)-1H-quinolin-4-one 
• 1621002-88-7 C₂₄H₂₁NO₃ 
• 1621002-91-2 7-hydroxy-3-(4-hydroxyphenyl)-1H-quinolin-4-one 
• 1621002-92-3 7-hydroxy-3-(4-hydroxyphenyl)-1-methyl-1H-quinolin-4-one 
• 1621002-98-9 C₂₂H₂₃NO₃ 
• 1621002-93-4 7-hydroxy-3-(4-hydroxyphenyl)-1-ethyl-1H-quinolin-4-one 
• 1621002-94-5 7-hydroxy-3-(4-hydroxyphenyl)-1-propyl-1H-quinolin-4-one 
• 1621002-95-6 7-hydroxy-3-(4-hydroxyphenyl)-1-(3-methylbutyl)-1H-quinolin-4-one 

Relevant articles and documents

Design and synthesis of azaisoflavone analogs as phytoestrogen mimetics

A series of azaisoflavone analogs were designed and synthesized and their transactivation activities and binding affinities for ERα and ERβ were investigated. Among these compounds, 2b and 3a were the most potent with 6.5 and 1.1 μM of EC50, respectively. Molecular modeling study showed putative binding modes of the compound 3a in the active site of ERα and ERβ, which were similar with that of genistein and provided insight of the effect of N-alkyl substitution of azaisoflavones on ERβ activity. Also, a biphasic effect of azaisoflavone analogs on MCF-7 cell growth depending on their concentrations was investigated.