105337-34-6

Basic information

• Product Name: 2-hydroxy-3-isopropyl-6-methylphenyl methyl ketone
• Synonyms: 2-hydroxy-3-isopropyl-6-methylphenyl methyl ketone
• CAS NO: 105337-34-6
• Molecular Weight: 192.258
• Mol File: 105337-34-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-3-isopropyl-6-methylphenyl methyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-isopropyl-6-methylphenyl methyl ketone(105337-34-6)
• EPA Substance Registry System: 2-hydroxy-3-isopropyl-6-methylphenyl methyl ketone(105337-34-6)

Safety Data

• Hazardous Substances Data: 105337-34-6(Hazardous Substances Data)

Upstream product

• 89-83-8 thymol 
• 75-36-5 acetyl chloride 
• 528-79-0 2-isopropyl-5-methylphenyl acetate 

Relevant articles and documents

Regioselective fries rearrangement and friedel-crafts acylation as efficient routes to novel enantiomerically enriched ortho-acylhydroxy[2.2]paracyclophanes

Two useful approaches to ortho-acylhydroxy[2.2]paracyclophanes, starting from 4-hydroxy[2.2]paracyclophane, have been developed. TiCl4-catalyzed Fries rearrangement and direct acylation occur regioselectively (to the ortho position with respect to the hydroxy group), leading to 4-acetyl-5-hydroxy[2.2]paracyclophane (3) and 4-benzoyl-5-hydroxy[2.2]-paracyclophane (4) in high to excellent chemical yields. For compound 4, an X-ray investigation has been performed. ortho-Acylhydroxy[2.2]paracyclophanes 3 and 4 have been obtained in enantiomerically enriched forms (ee 92-99%) and the absolute configurations of their enantiomers have been determined.