105357-89-9

Basic information

• Product Name: Ethanone, 1-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-
• CAS NO: 105357-89-9
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Mol File: 105357-89-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-(105357-89-9)
• EPA Substance Registry System: Ethanone, 1-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-(105357-89-9)

Safety Data

• Hazardous Substances Data: 105357-89-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 3508-78-9 3-allyl-2,4-pentanedione 
• 123-54-6 acetylacetone 
• 26567-78-2 (Z)-4-(phenylamino)-3-penten-2-one 
• 38352-74-8 3-acetylhex-5-yn-2-one 
• 83-24-9 2,5-dimethyl-1-phenyl-1H-pyrrole 
• 127-19-5 N,N-dimethyl acetamide 

Downstream Products

• 1260237-23-7 anilino(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)acetonitrile 

Relevant articles and documents

Efficient synthesis of substituted pyrroles through iron-mediated oxidation reaction of 3-methylenehexane-2,5-dione with primary amines

An efficient route has been developed for the synthesis of multiple substituted pyrrole derivatives from the readily available agents through iron-mediated oxidative aromatization process in good to excellent yields. This method is well tolerated with a diverse broad range of substrates and a complementary approach to currently available synthetic methods.

Silver-catalysed hydroamination: Synthesis of functionalised pyrroles

It has been shown that functionalised pyrroles can be efficiently prepared using a two-step sequence. This sequence involves the propargylation of secondary enaminones using n-BuLi and propargyl bromide, followed by intramolecular hydroamination catalysed by silver nitrate. The hydroamination can be carried out at room temperature (overnight) or in a domestic microwave oven (60 s).

Gold-Catalyzed Sequential Amination/Annulation Reactions of 2-Propynyl-1,3-dicarbonyl Compounds

The gold(III)-catalyzed sequential amination/annulation reaction of 2-propynyl-1,3-dicarbonyl compounds 1 with primary amines 2 produces 1,2,3,5-substituted pyrroles 4 in moderate to high yields.