1053628-87-7

Basic information

• Product Name: 2-fluoro-6-N,N-dibenzoyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine
• Synonyms: 2-fluoro-6-N,N-dibenzoyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine
• CAS NO: 1053628-87-7
• Molecular Weight: 805.776
• Mol File: 1053628-87-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-fluoro-6-N,N-dibenzoyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-6-N,N-dibenzoyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine(1053628-87-7)
• EPA Substance Registry System: 2-fluoro-6-N,N-dibenzoyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine(1053628-87-7)

Safety Data

• Hazardous Substances Data: 1053628-87-7(Hazardous Substances Data)

Upstream product

• 854158-99-9 2-nitro-pentabenzoyl adenosine 
• 98-88-4 benzoyl chloride 
• 58-61-7 adenosine 
• 62374-23-6 N⁶,N⁶,2',3',5'-pentabenzoyl-β-D-adenosine 

Downstream Products

• 146-78-1 2-fluoroadenosine 

Relevant articles and documents

METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF

The present invention relates to a method for preparing a 2-fluoropurine marked with the radioisotope 18F comprising a fluorination step for a 2-nitropurine derivative. The present invention comprises a 2-fluoropurine derivative marked with the radioisotope 18F which can be obtained by or during a method according to the invention and its various uses.

A novel method for the introduction of fluorine into the purine 2-position: Synthesis of 2-fluoroadenosine and a formal synthesis of the antileukemic drug fludarabine

A novel method for the introduction of fluorine in the purine 2-position is described and employed in the synthesis of a potential antimycobacterial compound. Also 2-fluoroadenosine has been synthesized for the first time from adenosine with perbenzoylated 2-nitroadenosine as a key intermediate. Mild reaction conditions are employed and few synthetic steps are required. The novel synthesis of fluoroadenosine can be regarded as a formal synthesis of the antileukemic drug fludarabine phosphate. Georg Thieme Verlag Stuttgart.