10537-08-3

Basic information

• Product Name: 2-chloro-9H-carbazole
• Synonyms: 2-chloro-9H-carbazole;2-Chlorocarbazole;2-chloroarbazole;2-Chloro-9H-carbazole
• CAS NO: 10537-08-3
• Molecular Formula: C₁₂H₈ClN
• Molecular Weight: 201.65162
• Mol File: 10537-08-3.mol
• Article Data: 25

Chemical Properties

• Melting Point: 244℃
• Boiling Point: 388.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.363±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 16.21±0.30(Predicted)
• CAS DataBase Reference: 2-chloro-9H-carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-9H-carbazole(10537-08-3)
• EPA Substance Registry System: 2-chloro-9H-carbazole(10537-08-3)

Safety Data

• Hazardous Substances Data: 10537-08-3(Hazardous Substances Data)

Usage

Uses

2-Chloro-9H-carbazole is a useful research chemical.

Upstream product

• 36684-66-9 7-chloro-2,3,4,9-tetrahydro-1H-carbazole 
• 118-75-2 chloranil 
• 856794-35-9 6-chloro-1-phenyl-1H-benzotriazole 
• 101-17-7 3-chlorodiphenylamine 
• 56-23-5 tetrachloromethane 
• 86-74-8 9H-carbazole 
• 6271-80-3 4'-chloro-2-nitrobiphenyl 
• 2312-23-4 m-chlorophenylhydrazine hydrochloride 
• 108-94-1 cyclohexanone 
• 577-19-5 2-nitrophenyl bromide 
• 1679-18-1 4-Chlorophenylboronic acid 
• 4539-51-9 2-aminocarbazole 
• 615-43-0 2-iodophenylamine 
• 41513-04-6 2-chloro-5-bromonitrobenzene 

Downstream Products

• 86-79-3 2-hydroxycarbazole 
• 88590-00-5 2-phenyl-9H-carbazole 

Relevant articles and documents

Visible-light-driven Cadogan reaction

Visible-light-driven photochemical Cadogan-type cyclization has been discovered. The organic D-A type photosensitizer 4CzIPN found to be an efficient mediator to transfer energy from photons to the transient intermediate that breaks the barriers of deoxygenation in Cadogan reaction and enables a mild metal-free access to carbazoles and related heterocycles. DFT calculation results indicate mildly endergonic formation of the intermediate complex of nitrobiarenes and PPh3, which corresponds with experimental findings regarding reaction temperature. The robust synthetic capacity of the photoredox Cadogan reaction systems has been demonstrated by the viable productivity of a broad range of carbazoles and related N-heterocycles with good tolerance of various functionalities.

Synthesis of Carbazoles and Related Heterocycles from Sulfilimines by Intramolecular C?H Aminations

While direct nitrene insertions into C?H bonds have become an important tool for building C?N bonds in modern organic chemistry, the generation of nitrene intermediates always requires transition metals, high temperatures, ultraviolet or laser light. We report a mild synthesis of carbazoles and related building blocks through a visible light-induced intramolecular C?H amination reaction. A striking advantage of this new method is the use of more reactive aryl sulfilimines instead of the corresponding hazardous azides. Different catalysts and divergent light sources were tested. The reaction scope is broad and the product yield is generally high. An efficient gram-scale synthesis of Clausine C demonstrates the applicability and scalability of this new method.

Preparation of 2 - substituted oxazole compounds

The present invention belongs to the field of organic chemistry, and particularly relates to a preparation method for 2-substituted carbazole compounds. According to the preparation method provided by the present invention, the raw material source is wide, reaction operation and post-treatment are simple and convenient, the yield is high, the application range is wide, and the industrial production is facilitated.