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105440-01-5

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105440-01-5 Usage

Description

Norfloxacin EP Impurity H, also known as N-Ethoxycarbonyl Norfloxacin, is an impurity found in Norfloxacin, a fluorinated quinolone antibacterial drug. It is a derivative of pefloxacin and is characterized by its unique chemical structure, which includes a 7-[4-(Ethoxycarbonyl)piperazin-1-yl]-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid moiety.

Uses

Used in Pharmaceutical Industry:
Norfloxacin EP Impurity H is used as a reference compound for the quality control and standardization of Norfloxacin in the pharmaceutical industry. Its presence in the drug is essential for ensuring the purity, safety, and efficacy of the final product.
Used in Research and Development:
In the field of research and development, Norfloxacin EP Impurity H serves as a valuable tool for studying the properties, interactions, and potential applications of fluorinated quinolone antibacterials. It can be used to investigate the mechanisms of action, resistance, and optimization of these drugs for various medical applications.
Used in Quality Control and Regulatory Compliance:
Norfloxacin EP Impurity H is utilized in the quality control processes of pharmaceutical manufacturers to ensure that the final product meets the required standards and regulations. It helps in the detection and quantification of impurities, which is crucial for maintaining the safety and efficacy of the drug.
Used in Drug Development and Formulation:
In the development of new drugs and formulations, Norfloxacin EP Impurity H can be used as a starting material or a reference compound to guide the synthesis and optimization of novel fluorinated quinolone antibacterials. This can lead to the discovery of more effective and safer drugs for the treatment of bacterial infections.
Used in Analytical Chemistry:
Norfloxacin EP Impurity H is employed in analytical chemistry for the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) and mass spectrometry, for the detection and quantification of impurities in pharmaceutical products. This helps in ensuring the quality and consistency of the drugs in the market.

Check Digit Verification of cas no

The CAS Registry Mumber 105440-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,4,4 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 105440-01:
(8*1)+(7*0)+(6*5)+(5*4)+(4*4)+(3*0)+(2*0)+(1*1)=75
75 % 10 = 5
So 105440-01-5 is a valid CAS Registry Number.

105440-01-5 Well-known Company Product Price

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  • (1471583)  Norfloxacin Related Compound H  United States Pharmacopeia (USP) Reference Standard

  • 105440-01-5

  • 1471583-15MG

  • 14,500.98CNY

  • Detail

105440-01-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-ethoxycarbonyl NFLX

1.2 Other means of identification

Product number -
Other names 7-(4-Ethoxycarbonyl-piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105440-01-5 SDS

105440-01-5Downstream Products

105440-01-5Relevant articles and documents

Synthesis of some derivatives of 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)-3-quinolinecarb xylic acid (norfloxacin) as potential antibacterial agents

Pappalardo,Omodei-Sale,Zanuso

, p. 489 - 499 (2007/10/02)

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