1055197-64-2Relevant articles and documents
Synthesis and characterization of a smart contrast agent sensitive to calcium
Dhingra, Kirti,Maier, Martin E.,Beyerlein, Michael,Angelovski, Goran,Logothetis, Nikos K.
, p. 3444 - 3446 (2008)
A novel first-generation Ca2+ sensitive contrast agent, Gd-DOPTRA has been synthesized and characterized. The agent shows ~100% relaxivity enhancement upon addition of Ca2+. The agent is selective and sensitive to Ca2+ also in the presence of Mg2+ and Zn2+. The relaxivity studies carried out in physiological fluids prove the prospects of the agent for in vivo measurements. The Royal Society of Chemistry.