10558-44-8

Basic information

• Product Name: BIS(2-THIENYL) KETOXIME
• Synonyms: DI(2-THIENYL)METHANONE OXIME;BIS(2-THIENYL) KETOXIME;BIS(THIEN-2-YL)KETONE OXIME;Di-2-thienyl ketoxime, 97%;dithiophen-2-ylmethanone oxime
• CAS NO: 10558-44-8
• Molecular Formula: C₉H₇NOS₂
• Molecular Weight: 209.29
• Mol File: 10558-44-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 134 °C
• Boiling Point: 361.1 °C at 760 mmHg
• Flash Point: 172.2 °C
• Appearance: /
• Density: 1.38 g/cm³
• Vapor Pressure: 7.58E-06mmHg at 25°C
• Refractive Index: 1.698
• PKA: 10.49±0.70(Predicted)
• CAS DataBase Reference: BIS(2-THIENYL) KETOXIME(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(2-THIENYL) KETOXIME(10558-44-8)
• EPA Substance Registry System: BIS(2-THIENYL) KETOXIME(10558-44-8)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 10558-44-8(Hazardous Substances Data)

Usage

General Description

BIS(2-THIENYL) KETOXIME is a chemical compound with the molecular formula C8H7NOS. It is a pale yellow solid at room temperature and is used as an analytical reagent in various chemical tests. BIS(2-THIENYL) KETOXIME is also known for its ability to form stable complex compounds with metals, making it useful in metal ion analysis and determination. It is commonly used in industries such as pharmaceuticals, cosmetics, and agriculture for its versatile applications in chemical analysis and metal complexation. Additionally, BIS(2-THIENYL) KETOXIME may also have potential applications in organic synthesis and coordination chemistry due to its unique chemical properties.

InChI:InChI=1/C9H7NOS2/c11-10-9(7-3-1-5-12-7)8-4-2-6-13-8/h1-6,11H

Upstream product

• 6973-84-8 2-[α-(2-thienyl)-α-hydroxymethyl]thiophene 
• 98-03-3 thiophene-2-carbaldehyde 
• 704-38-1 di(thiophen-2-yl)methanone 
• 5470-11-1 hydroxylamine hydrochloride 

Downstream Products

• 1131328-99-8 bis(2-thienyl)ketone O-pentafluorobenzoyl oxime 
• 261925-40-0 di(2-thiophenyl)methylamine 

Relevant articles and documents

Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines

An enantioselective C-H iodination reaction using a mono-N-benzoyl- protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA): and the pharmaceutically acceptable salts and solvates thereof. D and E are different groups wherein one is N and the other is CR50. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA.