1056157-47-1Relevant articles and documents
Palladium-Catalyzed Hydroamidocarbonylation of Olefins to Imides
Li, Haoquan,Dong, Kaiwu,Neumann, Helfried,Beller, Matthias
, p. 10239 - 10243 (2015)
Carbonylation reactions allow the efficient synthesis of all kinds of carbonyl-containing compounds. Here, we report a straightforward synthesis of various imides from olefins and CO for the first time. The established hydroamidocarbonylation reaction affords imides in good yields (up to 90%) and with good regioselectivity (up to 99:1) when applying different alkenes and amides. The synthetic potential of the method is highlighted by the synthesis of Aniracetam by intramolecular hydroamidocarbonylation.