105631-63-8

Basic information

• Product Name: ethyl (2R,3S)-benzoyloxy-3-hydroxybutanoate
• CAS NO: 105631-63-8
• Molecular Weight: 252.267
• Mol File: 105631-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2R,3S)-benzoyloxy-3-hydroxybutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2R,3S)-benzoyloxy-3-hydroxybutanoate(105631-63-8)
• EPA Substance Registry System: ethyl (2R,3S)-benzoyloxy-3-hydroxybutanoate(105631-63-8)

Safety Data

• Hazardous Substances Data: 105631-63-8(Hazardous Substances Data)

Upstream product

• 582-25-2 Potassium benzoate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 4620-46-6 benzoic acid 1-ethoxycarbonyl-2-oxopropyl ester 

Relevant articles and documents

Highly Enantioselective Reduction of Ethyl 2-Acyloxy-3-oxobutanoate with Immobilized Baker's Yeast

Reduction of ethyl 2-acetoxy-3-oxobutanoate (4a) with immobilized baker's yeast in calcium alginate gel gave a 18:19:63 mixture of ethyl (2R,3S)- and (2S,3S)-2-acetoxy-3-hydroxybutanoates and ethyl (2S,3S)-2,3-dihydroxybutanoate each with >95percent e.e. in 58percent yield.A similar treatment of a 2-benzoyloxy analog of 4a afforded a 6:94 mixture of ethyl (2R,3S)- and (2S,3S)-2-benzoyloxybutanoates (>95percent e.e.) in 70percent yield.Their absolute configurations were determined by comparison with authentic (2R,3S)- and (2S,3S)-2,3-dihydroxybutanoic acids.Effects of the immobilization and the pH of culture solution on the product ratio are also discussed.