10564-55-3

Basic information

• Product Name: Benzene, 1-[(isocyanatomethyl)sulfonyl]-4-methyl-
• CAS NO: 10564-55-3
• Molecular Formula: C9H9NO3S
• Molecular Weight: 211.241
• Mol File: 10564-55-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(isocyanatomethyl)sulfonyl]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(isocyanatomethyl)sulfonyl]-4-methyl-(10564-55-3)
• EPA Substance Registry System: Benzene, 1-[(isocyanatomethyl)sulfonyl]-4-methyl-(10564-55-3)

Safety Data

• Hazardous Substances Data: 10564-55-3(Hazardous Substances Data)

Upstream product

• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 28126-30-9 N-Toluol-4-sulfonylmethyl-thiocarbaminsaeure-S-ethylester 

Downstream Products

• 40939-26-2 {[(4-methylphenyl)sulfonyl]methyl}carbonimidic dichloride 
• 1014-23-9 5-(4-nitrophenyl)oxazole 
• 1585988-02-8 isopropyl (tosylmethyl)carbamate 
• 1585988-03-9 cyclohexyl (tosylmethyl)carbamate 
• 1585988-04-0 C₃₆H₅₅NO₄S 
• 1585988-05-1 S-butyl (tosylmethyl)carbamothioate 
• 1585988-06-2 C₁₃H₂₀N₂O₃S 
• 76758-16-2 N-tosylmethyl-N'-tert-butylurea 
• 1585988-07-3 C₁₃H₁₈N₂O₃S 
• 401647-49-2 C₁₅H₁₆N₂O₃S 
• 1585988-08-4 C₁₅H₁₇N₃O₃S 
• 14674-22-7 N?{[(4?methylphenyl)sulfonyl]methyl}benzamide 
• 1585988-09-5 C₁₅H₁₄FNO₃S 
• 1585988-10-8 C₁₉H₁₇NO₃S 

Relevant articles and documents

Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: Utility in synthetic and medicinal chemistry

A convenient and efficient (one-step) oxidation is reported of commercially available tosylmethylisocyanide (TOSMIC) to form tosylmethylisocyanate, making this highly reactive bifunctional molecule a readily available synthetic reagent. Besides engaging in nucleophilic addition reactions with alcohols, amines, and thiols, tosylmethylisocyanate also reacts with carboxylic acids to form tosylmethylamides, which undergo substitution reactions in the presence of organocopper and organomagnesium reagents.