1056614-85-7Relevant articles and documents
Organocatalytic enantioselective oxidative C-H alkenylation and arylation of N-Carbamoyl tetrahydropyridines and tetrahydro-β-carbolines
Liu, Xigong,Meng, Zhilin,Li, Chengkun,Lou, Hongxiang,Liu, Lei
, p. 6012 - 6015 (2015)
The first organocatalytic enantioselective C-H alkenylation and arylation reactions of N-carbamoyl tetrahydropyridines and tetrahydro-β-carbolines (THCs) are described. The metal-free processes represent an efficient and straightforward approach to a variety of structurally and electronically diverse α-substituted tetrahydropyridines and THCs in good yields with excellent regio- and enantioselectivities. Preliminary control experiments provide important insights into the reaction mechanism.
