105663-25-0

Basic information

• Product Name: (1S,2S)-trans-1,2-cyclohexanediol diacetate
• Synonyms: (1S,2S)-trans-1,2-cyclohexanediol diacetate
• CAS NO: 105663-25-0
• Molecular Weight: 200.235
• Mol File: 105663-25-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (1S,2S)-trans-1,2-cyclohexanediol diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-trans-1,2-cyclohexanediol diacetate(105663-25-0)
• EPA Substance Registry System: (1S,2S)-trans-1,2-cyclohexanediol diacetate(105663-25-0)

Safety Data

• Hazardous Substances Data: 105663-25-0(Hazardous Substances Data)

Upstream product

• 244056-56-2 (1S,2S,2'R,2''R,6'R,6''R)-1,2-O-<6',6''-Bis(hydroxymethyl)-3',3'',4',4'',5',5'',6',6''-octahydro-2',2''-bi(2H-pyran-2',2''-diyl)>cyclohexane-1,2-diol 
• 1460-57-7 trans-1,2-cyclohexandiol 
• 57794-08-8 (1S,2S)-trans-1,2-Cyclohexanediol 
• 108-24-7 acetic anhydride 
• 1759-71-3 trans-1,2-cyclohexanediol diacetate 
• 108-22-5 Isopropenyl acetate 

Downstream Products

• 57794-08-8 (1S,2S)-trans-1,2-Cyclohexanediol 

Relevant articles and documents

Adrenaline profiling of lipases and esterases with 1,2-diol and carbohydrate acetates

The adrenaline test for enzymes is a general back-titration procedure to detect 1,2-diols, 1,2-aminoalcohols and α-hydroxyketones reaction products of enzyme catalysis by colorimetry. The method was used to profile a series of esterases and lipases for their esterolytic activity on a series of carbohydrate and polyol acetates. Substrates were prepared by peracetylation and used for parallel microtiter-plate analysis of enzyme activities. This method can be used to achieve a rapid and automated characterization of a set of enzymes during HTS screening.

Dispiroketals in synthesis. Part 24. Preparation and use of chiral 2,2′-bis(triisopropylsilyloxymethyl)bi(dihydropyran)s as new protecting and resolving agents for 1,2-diols

C2 symmetric chiral 2,2′-bis(triisopropylsilyloxymethyl)bi(dihydropyran)s (S,S)-1 and (R,R)-1 were prepared from the corresponding glycidols and selectively reacted with 1,2-diols to give dispiroketals. The products of these reactions could be deprotected following treatment with fluoride, oxidation and reductive cleavage with samarium(II) iodide.

Enantioselective acylation of primary and secondary alcohols catalyzed by lipase QL from Alcaligenes sp.: A predictive active site model for lipase QL to identify which enantiomer of an alcohol reacts faster in this acylation

Lipase QL (from Alcaligenes sp.)-catalyzed acylation of alcohols using isopropenyl acetate as the acylating agent in diisopropyl ether converted preferentially primary alcohols with an S configuration and secondary alcohols with an R configuration into the corresponding homochiral acetates. On the basis of observed enantiomer selectivities, a predictive active site model for lipase QL is proposed for identifying which enantiomer of a primary or a secondary alcohol reacts faster in this acylation. Copyright (C) 1996 Published by Elsevier Science Ltd.