10567-58-5

Basic information

• Product Name: dimethyl (2E)-2-(phenylamino)but-2-enedioate
• Synonyms: 2-Butenedioic acid, 2-(phenylamino)-, dimethyl ester, (2E)-; Dimethyl (2E)-2-anilinobut-2-enedioate
• CAS NO: 10567-58-5
• Molecular Formula: C₁₂H₁₃NO₄
• Molecular Weight: 235.2359
• Mol File: 10567-58-5.mol
• Article Data: 35

Chemical Properties

• Boiling Point: 356.7°C at 760 mmHg
• Flash Point: 169.5°C
• Density: 1.226g/cm³
• Vapor Pressure: 2.87E-05mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: dimethyl (2E)-2-(phenylamino)but-2-enedioate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (2E)-2-(phenylamino)but-2-enedioate(10567-58-5)
• EPA Substance Registry System: dimethyl (2E)-2-(phenylamino)but-2-enedioate(10567-58-5)

Safety Data

• Hazardous Substances Data: 10567-58-5(Hazardous Substances Data)

Upstream product

• 553-90-2 Dimethyl oxalate 
• 124-41-4 sodium methylate 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 25007-54-9 Dimethyl 2-oxosuccinate 
• 62-53-3 aniline 

Downstream Products

• 251986-52-4 4,5-dimethoxycarbonyl-1-phenyl-1H-pyrrole-2,3-dione 
• 7101-89-5 4-oxo-1,4-dihydroquinoline-2-carboxylic acid methyl ester 
• 906463-83-0 4-phenyl-quinoline-2-carboxylic acid methyl ester 
• 13797-22-3 methyl N-phenyloxamate 

Relevant articles and documents

Substituent effect of ancillary ligands on the luminescence of bis[4,6-(di-fluorophenyl)-pyridinato-N,C2′]iridium(iii) complexes

Two series of (dfppy)2Ir(LN^O) with different substituents were designed and successfully synthesized and the effect of substitution at the ancillary ligand on the photophysical and electrochemical properties of (dfppy)2Ir

Base-Catalyzed Tandem Cyclization: Diastereoselective Access to the 3,4-Dihydroisoquinolin-2(1 H)-one Core

A novel, one-pot reaction for the synthesis of 3,4-dihydroisoquinolin-2(1 H)-one derivatives is developed via a base-mediated three-component reaction of ninhydrin, aniline and acetylenic esters. This diastereoselective reaction takes place in methanol at 70A °C under transition-metal-free conditions, and direct construction of the C-N and C-C bonds is readily achieved via tandem cyclization. These cyclic frameworks are resourceful small molecular keys to many natural products.

Trifluoroacetic acid catalyzed one-pot four-component domino reaction for the synthesis of substituted dihydro 2-oxypyrroles

Trifluoroacetic acid was applied as an effcient catalyst for the one-pot four-component synthesis of N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates via the domino reaction of amines, formaldehyde and dialkyl acetylenedicarboxylates at ambient temp

Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria

Synthesis of a recently discovered S-methylated quinolone natural product (1) was carried out, in addition to the production of a range of 2-substituted 4-quinolone derivatives (2-11). Two approaches were used: (i) the base-catalyzed cyclization of N-(ket

One-pot synthesis of 2,4-disubstituted quinolines via silver-catalyzed three-component cascade annulation of amines, alkyne esters and terminal alkynes

Described herein is a new and general method for one-pot synthesis of 2,4-disubstituted quinolines via silver-catalyzed [3 + 1 + 2] annulation of simple amines, alkyne esters and terminal alkynes. The versatile transformation might initiate with the facil