1057214-93-3

Basic information

• Product Name: 5-phenyl-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
• Synonyms: 5-phenyl-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
• CAS NO: 1057214-93-3
• Molecular Weight: 311.427
• Mol File: 1057214-93-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-phenyl-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide(1057214-93-3)
• EPA Substance Registry System: 5-phenyl-1H-pyrrole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide(1057214-93-3)

Safety Data

• Hazardous Substances Data: 1057214-93-3(Hazardous Substances Data)

Upstream product

• 6636-06-2 5-phenyl-1H-pyrrole-2-carboxylic acid 
• 127285-08-9 4-amino-1-isopropylpiperidine 

Relevant articles and documents

Pyrrole-derivatives as factor Xa inhibitors

The present invention relates to compounds of the formulae I and Ia, wherein R0 ; R1 ; R2 ; R3 ; R4; R22, Q; V, G and M have the meanings indicated in the claims. The compounds of the formulae I and Ia are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formulae I and Ia, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.