10581-07-4Relevant articles and documents
Organocatalyzed synthesis of ureas from amines and ethylene carbonate
Saliu, Francesco,Rindone, Bruno
, p. 6301 - 6304 (2010)
A new solventless method for the synthesis of symmetrical and unsymmetrical ureas, starting from ethylene carbonate and amines, is reported. 1,5,7-Triazabicyclo[4.4.0]dec-5-ene(TBD) and thioureas have been found to be efficient organocatalysts for this reaction.
N-carbonylation of lithium azaenolates of amides, formamides, ureas, and carbamates with carbon monoxide mediated by selenium
Fujiwara, Shin-Ichi,Okada, Kazuhiro,Shikano, Yasukazu,Shimizu, Yoshihiko,Tsutomu, Shin-Ike,Terao, Jun,Kambe, Nobuaki,Sonoda, Noboru
, p. 273 - 276 (2007)
N-Carbonylation of less nucleophilic nitrogen compounds was achieved by the reaction of the lithium azaenolates with carbon monoxide and selenium. This reaction proceeds in the cases of amides, formamides, ureas, and carbamates, leading to the formation of the corresponding carbamosele-noates in good to high yields after trapping with BuI.
Highly efficient synthesis of ureas and carbamates from amides by iodosylbenzene-induced hofmann rearrangement
Liu, Peng,Wang, Zhiming,Hu, Xianming
experimental part, p. 1994 - 2000 (2012/05/05)
A simple and efficient method for the synthesis of 1,3-disubstituted ureas and carbamates from amides by using iodosylbenzene as the oxidant is described. Symmetric and asymmetric ureas and carbamates can be prepared by this procedure in up to 98 % yield. Ureidopeptides can also be prepared in good yield by this method. A simple and efficient method for the synthesis of 1,3-disubstituted ureas and carbamates from amides by using iodosylbenzene as the oxidant is described. By using this method, heterocyclic products can be easily obtained in excellent yield. Ureidopeptides can also be prepared in good yield by this procedure. Copyright
