1058163-35-1Relevant articles and documents
Synthesis, characterization, and antioxidant activity of some new benzodiazepine derivatives
Bhat, K. Ishwar,Kumar, Abhishek
, p. 397 - 400 (2018/09/29)
A series of novel 4-(substituted phenyl)-2-(2-thienyl)-2,3-dihydro-1H-benzo[b] [1,4] diazepines (MB1-MB8) has been synthesized from 3-(substituted phenyl)-1-(2-thienyl)prop-2-en-1ones (MC1-MC8). The latter compo
Ga(OTf)3-promoted condensation reactions for 1,5-benzodiazepines and 1,5-benzothiazepines
Pan, Xiang-Qiang,Zou, Jian-Ping,Huang, Zhi-Hao,Zhang, Wei
, p. 5302 - 5308 (2008/12/22)
Condensation reactions of o-phenylenediamine and two equivalents of acetophenone under gallium(III) triflate catalysis produce biaryl-substituted 1,5-benzodiazepines. Similar reactions of o-phenylenediamine or o-aminothiophenol and o-hydroxy chalcones lead to formation of functionalized 1,5-benzodiazepines and 1,5-benzothiazepines in good to excellent yields. The ortho-hydoxy group of chalcones is crucial for this unprecedented condensation process.