1059176-76-9Relevant articles and documents
Synthesis and anti-platelet activity of obovatol derivatives
Kwak, Jae-Hwan,Lee, Seul,Park, Eun-Seok,In, Jin-Kyung,Song, Jiho,Kim, Young Jin,Choi, Nam Song,Lee, Heesoon,Yun, Yeo-Pyo,Hong, Jin Tae,Kwak, Young-Shin,Min, Kyung Hoon,Jung, Jae-Kyung
, p. 1107 - 1112 (2011)
Obovatol derivatives were synthesized and evaluated for anti-platelet activity. Three derivatives (1, 2, 4i) displayed equipotent activity to obovatol in arachidonic acid-induced platelet aggregation. An initial SAR study revealed that the introduction of alkoxy group in B ring could enhance inhibitory activity.