105929-28-0

Basic information

• Product Name: (R)-2-methoxy-2-phenylacetamide
• Synonyms: (R)-2-methoxy-2-phenylacetamide
• CAS NO: 105929-28-0
• Molecular Weight: 165.192
• Mol File: 105929-28-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-methoxy-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-methoxy-2-phenylacetamide(105929-28-0)
• EPA Substance Registry System: (R)-2-methoxy-2-phenylacetamide(105929-28-0)

Safety Data

• Hazardous Substances Data: 105929-28-0(Hazardous Substances Data)

Upstream product

• 3966-32-3 (R)-methoxyphenylacetic acid 
• 32174-46-2 methyl (R)-(-)-2-methoxy-2-phenylacetate 

Downstream Products

• 3524-62-7 benzoin monomethyl ether 

Relevant articles and documents

Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E

The dehydration reaction of aldoximes and amides for the synthesis of nitriles using [Et2NSF2]BF4 (XtalFluor-E) is described. Overall, the reaction proceeds rapidly (normally 1 h) at room temperature in an environmentally benign solvent (EtOAc) with only a slight excess of the dehydrating agent (1.1 equiv). A broad scope of nitriles can be prepared, including chiral nonracemic ones. In addition, in a number of cases, further purification of the nitrile after the workup was not required.