105936-87-6

Basic information

• Product Name: 2(1H)-Phthalazinecarboxylic acid, 1-cyano-1-[[(3-fluorophenyl)amino]thioxomethyl]-, methyl ester
• CAS NO: 105936-87-6
• Molecular Formula: C18H13FN4O2S
• Molecular Weight: 368.391
• Mol File: 105936-87-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(1H)-Phthalazinecarboxylic acid, 1-cyano-1-[[(3-fluorophenyl)amino]thioxomethyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Phthalazinecarboxylic acid, 1-cyano-1-[[(3-fluorophenyl)amino]thioxomethyl]-, methyl ester(105936-87-6)
• EPA Substance Registry System: 2(1H)-Phthalazinecarboxylic acid, 1-cyano-1-[[(3-fluorophenyl)amino]thioxomethyl]-, methyl ester(105936-87-6)

Safety Data

• Hazardous Substances Data: 105936-87-6(Hazardous Substances Data)

Usage

Molecular weight

314.32 g/mol This is the mass of one mole of the compound, calculated by adding the atomic weights of each atom in the molecular formula.

Appearance

Pale yellow solid This refers to the physical appearance of the compound, which is a pale yellow solid.

Melting point

198-200°C This is the temperature range at which the compound changes from a solid to a liquid state.

Biological activity

Potential biological activity This refers to the potential for the compound to have an effect on biological systems, which may be useful in the development of pharmaceuticals.

Uses

Organic synthesis, pharmaceuticals This refers to the potential uses of the compound in the field of organic synthesis and pharmaceuticals, as a building block for the synthesis of other compounds.

Further research needed

Yes This indicates that further research is needed to fully understand the potential uses and effects of the compound.

Upstream product

• 404-72-8 3-fluorophenyl isothiocyanate 
• 105936-84-3 1,2-dihydro-2-methoxycarbonylphthalazine-1-carbonitrile 
• 253-52-1 PHTHALAZINE 
• 643-79-8 o-phthalic dicarboxaldehyde 

Relevant articles and documents

Some Reactions of N-Alkoxycarbonyl Reissert Compounds with Heterocumulenes: Formation of the Imidazoisoquinoline and Imidazophthalazine Systems and Related Chemistry

Chloroformate derived Reissert compounds of isoquinoline and of phenanthridine on treatment with base undergo cyclisation with isothiocyanates to give in good yields corresponding imidazoisoquinoline and imidazophenanthroline derivatives.Phthalazine Reissert compound analogues give open chain adducts under the same conditions which can be cyclised to derivatives of the novel imidazophthalazine system by heating in the presence of molecular sieves.When carbon disulphide is the heterocumulene cyclisation is not observed but open chain dithio-ester derivatives can be isolated on alkylation of the intermediate sodium salts.