105942-10-7

Basic information

• Product Name: 4-CYANO-2-FLUOROBENZALDEHYDE
• Synonyms: 4-CYANO-2-FLUOROBENZALDEHYDE;2-FLUORO-4-CYANOBENZALDEHYDE;Benzonitrile, 3-fluoro-4-formyl- (9CI);Benzonitrile, 3-fluoro-4-formyl-;3-Fluoro-4-formylbenzonitrile 99%;4-Cyano-2-fluorobenzaldehyde, 98%+
• CAS NO: 105942-10-7
• Molecular Formula: C₈H₄FNO
• Molecular Weight: 149.12
• Product Categories: HALIDE;ALDEHYDE;Drug Intermediates;Fluorine series
• Mol File: 105942-10-7.mol
• Article Data: 17

Chemical Properties

• Melting Point: 73.2-75
• Boiling Point: 275.8 °C at 760 mmHg
• Flash Point: 120.6 °C
• Appearance: /
• Density: 1.25 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-CYANO-2-FLUOROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-2-FLUOROBENZALDEHYDE(105942-10-7)
• EPA Substance Registry System: 4-CYANO-2-FLUOROBENZALDEHYDE(105942-10-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 105942-10-7(Hazardous Substances Data)

Usage

General Description

4-CYANO-2-FLUOROBENZALDEHYDE is a chemical compound with the molecular formula C8H5FNO. It is a yellow powder that is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. 4-CYANO-2-FLUOROBENZALDEHYDE is known for its strong and characteristic odor, and it is classified as a hazardous chemical due to its potential for causing irritation to the eyes, skin, and respiratory system upon exposure. It is important to handle and store 4-CYANO-2-FLUOROBENZALDEHYDE with caution and in compliance with safety guidelines.

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 164149-28-4 4-cyano-2-fluorobenzoic acid 
• 175596-01-7 methyl 4-cyano-2-fluorobenzoate 
• 105-07-7 4-cyanobenzaldehyde 
• 133059-44-6 4-bromo-3-fluorobenzonitrile 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 1313-13-9 manganese dioxide 
• 219873-06-0 3-fluoro-4-(hydroxymethyl)benzonitrile 
• 87413-09-0 Dess-Martin periodane 
• 59189-97-8 3-fluoro-4-methylbenzoic acid chloride 
• 350-28-7 3-fluoro-4-methyl-benzoic acid 
• 170572-49-3 2-fluoro-4-cyanotoluene 
• 105942-09-4 4-(bromomethyl)-3-fluorobenzonitrile 

Downstream Products

• 170726-99-5 3-Fluoro-4-(hydroxyimino-methyl)-benzonitrile 
• 84102-89-6 4-formyl-3-hydroxybenzonitrile 
• 1164201-95-9 (4S)-4-{4-cyano-2-(methylsulfinyl)phenyl}-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carbonitrile 

Relevant articles and documents

METHOD FOR PRODUCING (4S)-4-[4-CYANO-2-(METHYLSULFONYL)PHENYL]-3,6-DIMETHYL-2-OXO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,3,4-TETRAHYDRO PYRIMIDINE-5-CARBONITRILE

The present invention concerns a new and improved method for preparation of (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluormethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), as well as the preparation a

NOVEL AROMATIC COMPOUND AND USE THEREOF

Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or To treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.

SULFONIC AMIDE AND SULFOXIMINE-SUBSTTTUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF

The present application relates to novel sulfonamidw- or sulfoximine-substituted 1,4-diaryldihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and als