1059656-14-2

Basic information

• Product Name: (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester
• Synonyms: (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester
• CAS NO: 1059656-14-2
• Molecular Weight: 866.075
• Mol File: 1059656-14-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester(1059656-14-2)
• EPA Substance Registry System: (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester(1059656-14-2)

Safety Data

• Hazardous Substances Data: 1059656-14-2(Hazardous Substances Data)

Upstream product

• 145486-70-0 3-amino-3,4,5,6-tetrahydro-1H-1-benzazocin-2-one 
• 155300-46-2 N-(tert-butoxycarbonyl)-4,4-dimethylazetidin-2-one 
• 97278-72-3 3-azido-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one 
• 124750-53-4 N-triphenylmethyl-5-(4'-methylbiphenyl-2-yl)tetrazole 
• 129765-95-3 3-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4879-95-2 4,4-dimethyl-azetidin-2-one 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 

Relevant articles and documents

A novel 3-substituted benzazepinone growth hormone secretagogue (L- 692,429)

The 3-substituted benzazepinone, L-692,429 (compound 1), is the prototype compound of a novel class of compounds that stimulate release of growth hormone (GH). The molecule evolved from efforts to identify a non-peptide mimic of the growth hormone-releasing hexapeptide, GHRP-6. Compound 1 is prepared by sequential attachment of dimethyl-β-alanine and 2'- biphenylyltetrazole side chains to a chiral 3-aminobenzolactam nucleus. Comparison of the biological activity of 1 with the corresponding six- and eight-membered lactam analogs shows the seven-membered benzazepinone skeleton to be preferred. Molecular modeling of the structurally diverse GH secretagogues, L-692,429 and GHRP-6, was performed.