105995-50-4Relevant articles and documents
PROCESS FOR THE PREPARATION OF CARBAPENEM COMPOUNDS
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Page/Page column 7-9, (2011/10/04)
The present invention relates to a process for the preparation of carbapenem compound of Formula (I), wherein P1 is hydrogen or a carboxyl protecting group, P3 is hydrogen or a hydroxyl protecting group, R1 is C1-3 alkyl, and A is selected from a group consisting of a) Formula (II), b) Formula (III), c) Formula (IV), d) Formula (V), e) Formula (VI), f) Formula (VII), wherein P2 is hydrogen or an amino protecting group, R2 and R3 may be same or different and are hydrogen, C1-5 alkyl, optionally substituted aryl, or optionally substituted heteroaryl, and X1 is O or S, or its stereoisomers, or salts thereof.
4-substituted 3-oxobutanoate ester derivatives
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, (2008/06/13)
This invention relates to a process for preparing 4-substituted 3-oxobutanoate ester derivatives by reaction of essentially anhydrous magnesium malonate monoester salts with activated acyl compounds.