106058-85-9

Basic information

• Product Name: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE
• Synonyms: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE;3-ACETYL-1-TOSYLPYRROLE;3-ACETYL-N-TOSYLPYRROLE;1-TOSYL-3-ACETYLPYRROLE;1-(1-Tosyl-1H-pyrrol-3-yl)ethanone;1-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-3-yl}ethanone;1-(4-Tolylsulfonyl)-3-acetylpyrrole
• CAS NO: 106058-85-9
• Molecular Formula: C₁₃H₁₃NO₃S
• Molecular Weight: 263.31
• Product Categories: Azoles;blocks
• Mol File: 106058-85-9.mol
• Article Data: 13

Chemical Properties

• Melting Point: 68-72°C
• Boiling Point: 88 °C
• Flash Point: 221.1 °C
• Appearance: /
• Density: 1.24 g/cm³
• Vapor Pressure: 5.18E-08mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: 2-8°C
• PKA: -11.38±0.70(Predicted)
• CAS DataBase Reference: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE(106058-85-9)
• EPA Substance Registry System: 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE(106058-85-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 106058-85-9(Hazardous Substances Data)

Usage

General Description

3-Acetyl-1-(p-tolylsulfonyl)pyrrole is a chemical compound with the molecular formula C15H15NO3S. It is a pyrrole derivative with a sulfonyl group attached to the p-tolyl group and an acetyl group at the 3-position. 3-Acetyl-1-(p-tolylsulfonyl)pyrrole is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various biologically active molecules. It possesses interesting pharmacological properties and has been studied for its potential therapeutic applications. Additionally, it can also be used as a reagent in chemical reactions and as a starting material for the synthesis of other compounds.

InChI:InChI=1/C13H13NO3S/c1-10-3-5-13(6-4-10)18(16,17)14-8-7-12(9-14)11(2)15/h3-9H,1-2H3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 70-55-3 toluene-4-sulfonamide 
• 152171-09-0 3-(1-hydroxyethyl)-1-tosylpyrrole 
• 117954-70-8 3-formyl-1-<(4-methylphenyl)sulfonyl>pyrrole 
• 7126-39-8 pyrrole-3-carboxaldehyde 

Downstream Products

• 158782-32-2 3-(1-hydroxy-1-phenylethyl)-1-tosylpyrrole 
• 1072-82-8 3-acetylpyrrole 
• 152171-09-0 3-(1-hydroxyethyl)-1-tosylpyrrole 
• 146072-89-1 1-<1-<1-(4-methylphenyl)sulfonyl>-3-pyrrolyl>-1,2-ethanediol 
• 144024-37-3 3-(1,3-dioxolan-2-yl)-1-<1-<(4-methylphenyl)sulfonyl>-3-pyrrolyl>-1-propanone 
• 146072-92-6 3-(1,3-dioxolan-2-yl)-1-<1-<(4-methylphenyl)sulfonyl>-3-pyrrolyl>-1-propanol 
• 146072-96-0 1-[1,3]Dioxolan-2-yl-4,4-dimethyl-3-[1-(toluene-4-sulfonyl)-1H-pyrrol-3-yl]-hex-5-en-3-ol 

Relevant articles and documents

Synthesis and polymerization of 2-(3-pyrrolyl)acetic acid derivatives from pyrrole

The synthesis of the 3-pyrrylacetic acid as well as the study of its esterification conditions are described. The new materials thus obtained are electropolymerized.

Asymmetric Organocatalytic Synthesis of Bisindoles – Scope and Derivatizations

Starting from 3-vinylindoles and glyoxolate imines, we created a library of diverse 4,6-bis(1H-indole-3-yl)piperidine 2-carboxylates by using 10 mol-% of a chiral phosphoric acid. Utilising electron-withdrawing groups on the starting material during the r

Gold(I)-catalyzed dearomative rautenstrauch rearrangement: Enantioselective access to cyclopenta[ b ]indoles

A highly enantioselective dearomative Rautenstrauch rearrangement catalyzed by cationic (S)-DTBM-Segphosgold(I) is reported. This reaction provides a straightforward method to prepare enantioenriched cyclopenta[b]indoles. These studies show vast differenc