1060671-67-1

Basic information

• Product Name: 2-{2-[1-(toluene-4-sulphonyl)-1H-indol-2-yl]ethyl}isoindole-1,3-dione
• Synonyms: 2-{2-[1-(toluene-4-sulphonyl)-1H-indol-2-yl]ethyl}isoindole-1,3-dione
• CAS NO: 1060671-67-1
• Molecular Weight: 444.511
• Mol File: 1060671-67-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{2-[1-(toluene-4-sulphonyl)-1H-indol-2-yl]ethyl}isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[1-(toluene-4-sulphonyl)-1H-indol-2-yl]ethyl}isoindole-1,3-dione(1060671-67-1)
• EPA Substance Registry System: 2-{2-[1-(toluene-4-sulphonyl)-1H-indol-2-yl]ethyl}isoindole-1,3-dione(1060671-67-1)

Safety Data

• Hazardous Substances Data: 1060671-67-1(Hazardous Substances Data)

Upstream product

• 14396-90-8 N-(3-butynyl)phthalimide 
• 61613-20-5 N-tosyl-2-iodoaniline 

Relevant articles and documents

Sonogashira/N-acyliminium ion aromatic π-cyclisation processes: access to tetra- and pentacyclic lactams

Application of the Sonogashira reaction of N-alkynylimides with 2-iodophenol or 2-iodo-N-tosylaniline affords 2-(N-alkylimino)-benzofurans and indoles in good yield. Selective partial reduction of the latter followed by treatment with TsOH generates N-acyliminium ions, which cyclise to afford tetra- and pentacyclic lactams in good yield. The latter are reduced to the analogous cyclic amines by BH3.