106109-81-3

Basic information

• Product Name: Propanoic acid, 3-[(4-methylphenyl)amino]-3-oxo-, methyl ester
• CAS NO: 106109-81-3
• Molecular Formula: C11H13NO3
• Molecular Weight: 207.229
• Mol File: 106109-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-[(4-methylphenyl)amino]-3-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-[(4-methylphenyl)amino]-3-oxo-, methyl ester(106109-81-3)
• EPA Substance Registry System: Propanoic acid, 3-[(4-methylphenyl)amino]-3-oxo-, methyl ester(106109-81-3)

Safety Data

• Hazardous Substances Data: 106109-81-3(Hazardous Substances Data)

Upstream product

• 624-31-7 4-tolyl iodide 
• 51513-29-2 methyl malonamate 

Relevant articles and documents

Ligand-Enabled Gold-Catalyzed C(sp2)-N Cross-Coupling Reactions of Aryl Iodides with Amines

The first example of ancillary (P,N)-ligand-enabled gold-catalyzed C-N cross-coupling reactions of aryl iodides with amines is reported. The high generality of the reaction in de novo synthesis, late-stage modifications, and cascade processes to access functionalized indolinones and carbazoles underscores the synthetic potential of the presented strategy. Monitoring the reaction with ESI-HRMS and NMR provided strong evidence for the in situ formation of putative high valent Au(III) intermediates.