1062132-47-1

Basic information

• Product Name: (R)-tert-butyl 3-(4-tert-butylbenzamido)piperidine-1-carboxylate
• Synonyms: (R)-tert-butyl 3-(4-tert-butylbenzamido)piperidine-1-carboxylate
• CAS NO: 1062132-47-1
• Molecular Weight: 360.497
• Mol File: 1062132-47-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 3-(4-tert-butylbenzamido)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 3-(4-tert-butylbenzamido)piperidine-1-carboxylate(1062132-47-1)
• EPA Substance Registry System: (R)-tert-butyl 3-(4-tert-butylbenzamido)piperidine-1-carboxylate(1062132-47-1)

Safety Data

• Hazardous Substances Data: 1062132-47-1(Hazardous Substances Data)

Upstream product

• 188111-79-7 tert-butyl (3R)3-aminopiperidine-1-carboxylate 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 1710-98-1 p-tert-butyl benzoyl chloride 

Downstream Products

• 1062132-59-5 (R)-4-tert-butyl-N-(piperidin-3-yl)benzamide 
• 1062131-41-2 (R)-N-(1-(7-(aminomethyl)-4-(4-(morpholine-4-carbonyl)phenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)-4-tert-butylbenzamide 
• 1062131-08-1 (R)-4-tert-butyl-N-(1-(7-cyano-4-(4-(morpholine-4-carbonyl)phenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)benzamide 
• 1062130-43-1 (R)-N-(1-(7-amino-4-(4-(morpholine-4-carbonyl)phenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)-4-tert-butylbenzamide 
• 1062128-03-3 (R)-4-tert-butyl-N-(1-(4-(4-(4-methylpiperazine-1-carbonyl)phenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)benzamide 
• 1062127-41-6 (R)-4-tert-butyl-N-(1-(4-(4-(morpholine-4-carbonyl)phenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)benzamide 
• 1062135-77-6 (R)-ethyl 4-(2-(3-(4-tert-butylbenzamido)piperidin-1-yl)imidazo[1,2-f][1,2,4]triazin-4-ylamino)benzoate 
• 1062128-56-6 (R)-4-tert-butyl-N-(1-(4-(4-carbamoylphenylamino)imidazo[1,2-f][1,2,4]triazin-2-yl)piperidin-3-yl)benzamide 

Relevant articles and documents

INHIBITORS OF BRUTON'S TYROSINE KINASE

Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other

HETEROCYCLIC AMIDES AS BTK INHIBITORS

Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/ or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.

FUSED HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE, ALLERGIC, AUTOIMMUNE OR INFLAMMATORY DISEASES

Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, [PLEASE INSERT CHEMICAL STRUCTURE HERE] (I) are useful as kinase modulators, including Btk modulation, wherein R1, R2, R4, Q, Y, A and D are as defined herein.