1062159-35-6

Basic information

• Product Name: WAY-600
• Synonyms: WAY-600;6-(1H-Indol-5-yl)-4-(4-morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine;6-(1H-indol-5-yl)-4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine;4-[6-(1H-indol-5-yl)-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]pyrazolo[3,4-d]pyrimidin-4-yl]morpholine
• CAS NO: 1062159-35-6
• Molecular Formula: C28H30N8O
• Molecular Weight: 494.5908
• Product Categories: PI3K/Akt/mTOR;Inhibitors;Akt;mTOR;PI3K
• Mol File: 1062159-35-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.43
• PKA: 16.08±0.30(Predicted)
• CAS DataBase Reference: WAY-600(CAS DataBase Reference)
• NIST Chemistry Reference: WAY-600(1062159-35-6)
• EPA Substance Registry System: WAY-600(1062159-35-6)

Safety Data

• Hazardous Substances Data: 1062159-35-6(Hazardous Substances Data)

Usage

General Description

WAY-600 is a novel dihydroorotate dehydrogenase (DHODH) inhibitor that has been developed as a potential anti-cancer agent. DHODH is an enzyme involved in the de novo pyrimidine biosynthesis pathway, and inhibition of this enzyme has been shown to disrupt cancer cell proliferation. Preclinical studies have demonstrated that WAY-600 has potent anti-proliferative activity against a variety of cancer cell lines, including breast, lung, and colon cancer. Additionally, WAY-600 has shown synergistic effects when combined with other anti-cancer agents, making it a promising candidate for further development as a cancer therapy.