1062242-20-9Relevant articles and documents
Iron-catalyzed cross-coupling reactions between a bicyclic alkenyl triflate and Grignard reagents
Le Marquand, Paul,Tsui, Gavin C.,Whitney, John C. C.,Tam, William
, p. 7829 - 7832 (2008)
(Chemical Equation Presented) Fe-catalyzed cross-coupling reactions between a bicyclic alkenyl triflate and Grignard reagents were investigated. Under the optimized reaction conditions, various 2-substituted bicyclic alkenes were synthesized in moderate to excellent yields (52-93%). This method provided an efficient route for the synthesis of 2-substituted bicyclic alkenes with 2° alkyl groups which cannot be synthesized using previous methods such as Pd-catalyzed coupling reactions and lithium-halide exchange reactions.