1062517-78-5

Basic information

• Product Name: (R)-(3-(2-methoxyphenyl)hept-1-yn-1-yl)trimethylsilane
• Synonyms: (R)-(3-(2-methoxyphenyl)hept-1-yn-1-yl)trimethylsilane
• CAS NO: 1062517-78-5
• Molecular Weight: 274.478
• Mol File: 1062517-78-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-(3-(2-methoxyphenyl)hept-1-yn-1-yl)trimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(3-(2-methoxyphenyl)hept-1-yn-1-yl)trimethylsilane(1062517-78-5)
• EPA Substance Registry System: (R)-(3-(2-methoxyphenyl)hept-1-yn-1-yl)trimethylsilane(1062517-78-5)

Safety Data

• Hazardous Substances Data: 1062517-78-5(Hazardous Substances Data)

Upstream product

• 1066-54-2 trimethylsilylacetylene 
• 75045-85-1 (+/-)-1-(trimethylsilyl)hept-1-yn-3-ol 
• 110-62-3 pentanal 
• 1357013-05-8 2,4,6-trimethoxyphenyl (1-(trimethylsilyl)hept-1-yn-3-yl) carbonate 
• 282727-20-2 (2-methoxyphenyl)zinc(II) iodide 
• 1062517-50-3 (±)-(3-bromohept-1-ynyl)trimethylsilane 

Relevant articles and documents

Nickel-catalyzed enantioselective cross-couplings of racemic secondary electrophiles that bear an oxygen leaving group

To date, effective nickel-catalyzed enantioselective cross-couplings of alkyl electrophiles that bear oxygen leaving groups have been limited to reactions of allylic alcohol derivatives with Grignard reagents. In this Communication, we establish that, in the presence of a nickel/pybox catalyst, a variety of racemic propargylic carbonates are suitable partners for asymmetric couplings with organozinc reagents. The method is compatible with an array of functional groups and utilizes commercially available catalyst components. The development of a versatile nickel-catalyzed enantioselective cross-coupling process for electrophiles that bear a leaving group other than a halide adds a significant new dimension to the scope of these reactions.