106268-14-8Relevant articles and documents
Preparation and Evaluation of Electrophilic Derivatives of Phenylbutazone as Inhibitors of Prostaglandin-H Synthase
Vennerstrom, Jonathan L.,Holmes, Thomas J.
, p. 563 - 567 (2007/10/02)
The chemical syntheses and biological evaluation of several potential irreversible inhibitors for prostaglandin (PGH) synthase are described.These inhibitors were modeled after the nonsteroidal antiinflammatory (NSAI) drug phenylbutazone(4-n-butyl-1,2-dip