106274-68-4

Basic information

• Product Name: 3-Amino-biphenyl-2-carbonitrile
• Synonyms: 3-amino-[1,1'-biphenyl]-2-carbonitrile
• CAS NO: 106274-68-4
• Molecular Formula: C₁₃H₁₀N₂
• Molecular Weight: 194
• Mol File: 106274-68-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Amino-biphenyl-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-biphenyl-2-carbonitrile(106274-68-4)
• EPA Substance Registry System: 3-Amino-biphenyl-2-carbonitrile(106274-68-4)

Safety Data

• Hazardous Substances Data: 106274-68-4(Hazardous Substances Data)

Usage

General Description

3-Amino-biphenyl-2-carbonitrile is a chemical compound consisting of a biphenyl ring with an amino group and a carbonitrile group attached at the 2-position. It is a white to light brown solid with a molecular formula C13H10N2. 3-Amino-biphenyl-2-carbonitrile is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also used in research and development as a building block for the creation of various organic compounds. The compound's chemical structure and properties make it useful in the production of a wide range of products, as well as in scientific investigations and studies.

Upstream product

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Relevant articles and documents

A comparative study of the recent most potent small-molecule PD-L1 inhibitors: what can we learn?

Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have become a “game-changer” in the cancer treatment. However, none of the small molecular inhibitors has been approved yet. To explore the advantages and disadvantages of various scaffolds, di

TBPB-initiated cascade cyclization of 3-arylethynyl-[1,1′-biphenyl]-2-carbonitriles with sulfinic acids: Access to sulfone-containing cyclopenta[: Gh] phenanthridines

A novel TBPB-initiated cascade cyclization of 3-arylethynyl-[1,1′-biphenyl]-2-carbonitriles with sulfinic acids via C-S, C-C and C-N bond formation for the synthesis of 3-sulfonated cyclopenta[gh]phenanthridines under metal-free conditions has been developed. This protocol features mild conditions, good functional group tolerance and a broad substrate scope. By using this protocol, a variety of potentially bioactive 3-sulfonated cyclopenta[gh]phenanthridines were facilely synthesized via direct annulation.

HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS

Disclosed are compounds of Formula (I′), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.