106315-28-0

Basic information

• Product Name: 1,25-dihydroxy-21-nor-20-oxavitamin D3
• Synonyms: 1,25-dihydroxy-21-nor-20-oxavitamin D3
• CAS NO: 106315-28-0
• Molecular Formula: C₂₅H₄₀O₄
• Molecular Weight: 404.5827
• Mol File: 106315-28-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 567°Cat760mmHg
• Flash Point: 296.7°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 3.24E-15mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 1,25-dihydroxy-21-nor-20-oxavitamin D3(CAS DataBase Reference)
• NIST Chemistry Reference: 1,25-dihydroxy-21-nor-20-oxavitamin D3(106315-28-0)
• EPA Substance Registry System: 1,25-dihydroxy-21-nor-20-oxavitamin D3(106315-28-0)

Safety Data

• Hazardous Substances Data: 106315-28-0(Hazardous Substances Data)

Usage

Type of compound

Synthetic derivative of vitamin D3

Function

Potent and selective agonist for the vitamin D receptor

Research use

Studying the effects of activating the vitamin D receptor

Therapeutic applications

Potential use in treating bone disorders, autoimmune diseases, and cancer

Effects

Similar to the natural hormone 1,25-dihydroxyvitamin D3, which regulates calcium and phosphorus levels in the body

Side effects

Potentially reduced side effects compared to the natural hormone

Additional properties

Anti-inflammatory and immunomodulatory properties

Future potential

Promising candidate for drug development

InChI:InChI=1/C25H40O4/c1-17-19(15-20(26)16-22(17)27)9-8-18-7-5-13-25(4)21(18)10-11-23(25)29-14-6-12-24(2,3)28/h8-9,20-23,26-28H,1,5-7,10-16H2,2-4H3/b18-8+,19-9+/t20-,21+,22+,23?,25+/m1/s1

Upstream product

• 106351-06-8 C₃₇H₄₉N₃O₈ 
• 106351-02-4 C₃₆H₅₈O₇ 
• 106351-05-7 Acetic acid (1S,3R,8S,9S,10R,13S,14S,17S)-3-acetoxy-17-(4-hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl ester 
• 81089-21-6 [1α,3β]-1,3-bis[(tetrahydro-2H-pyran-2-yl)oxy]androst-5-en-17-one 
• 106351-01-3 (1S,3R,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-1,3-bis-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol 
• 106351-07-9 (1S,3R,9S,10R,13S,14S,17S)-17-(4-Hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol 
• 106351-04-6 (1S,3R,8S,9S,10R,13S,14S,17S)-17-(4-Hydroxy-4-methyl-pentyloxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol 
• 106351-03-5 5-((1S,3R,8S,9S,10R,13S,14S,17S)-1,3-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yloxy)-pentan-2-one 
• 20998-18-9 1α,3β-dihydroxy-androst-5-en-17-one 
• 53-43-0 dehydroepiandrosterone 

Relevant articles and documents

Synthetic studies of vitamin D analogues. VII. Synthesis of 20-oxa-21-norvitamin D3 analogues

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