106351-16-0

Basic information

• Product Name: methyl 7α-mesyloxy-3β-tosyloxy-5α-cholanate
• CAS NO: 106351-16-0
• Molecular Weight: 638.887
• Mol File: 106351-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 7α-mesyloxy-3β-tosyloxy-5α-cholanate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 7α-mesyloxy-3β-tosyloxy-5α-cholanate(106351-16-0)
• EPA Substance Registry System: methyl 7α-mesyloxy-3β-tosyloxy-5α-cholanate(106351-16-0)

Safety Data

• Hazardous Substances Data: 106351-16-0(Hazardous Substances Data)

Upstream product

• 14772-97-5 methyl 3β,7α-dihydroxy-5α-cholan-24-oate 
• 106351-13-7 4β-bromo-7α-formyloxy-3-oxo-5β-cholanic acid 
• 106351-14-8 7α-formyloxy-3-oxo-4-cholenic acid 
• 106351-12-6 7α-formyloxy-3-oxo-5α-cholanic acid 
• 14772-95-3 7α-hydroxy-3-oxochol-4-en-24-oic acid 
• 124-63-0 methanesulfonyl chloride 
• 28192-93-0 methyl 7α-hydroxy-3β-tosyloxy-5α-cholanate 

Relevant articles and documents

POTENTIAL BILE ACID METABOLITES. X. SYNTHESES OF STEREOISOMERIC 3,7-DIHYDROXY-5α-CHOLANIC ACIDS

New synthetic routes to allochenodeoxycholic (3α,7α-dihydroxy-5α-cholanic) and alloursodeoxycholic (3α,7β-dihydroxy-5α-cholanic) acids, and their stereoisomers are described.Treatments of allo 7α-hydroxy-3β-tosyloxy ester with N,N-dimethylformamide and of allo 7α-mesyloxy-3β-tosyloxy and 3β-cathyloxy-7α-mesyloxy esters with potassium superoxide-crown ether afforded the desired 3α,7α-, 3α,7β-, and 3β,7β-dihydroxy stereoisomers, respectively, in high yield.Highperformance liquid chromatography was of key importance in characterizing the compounds and determining their purity.Keywords--bile acid; allo bile acid; 3,7-dihydroxy-5α-cholanic acid; allochenodeoxycholic acid; alloursodeoxycholic acid; N,N-dimethylformamide reaction; potassium superoxide-18-crown-6 ether reaction; HPLC