106364-45-8

Basic information

• Product Name: 2-(4-phenoxyphenyl)propanenitrile
• CAS NO: 106364-45-8
• Molecular Weight: 223.274
• Mol File: 106364-45-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-phenoxyphenyl)propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-phenoxyphenyl)propanenitrile(106364-45-8)
• EPA Substance Registry System: 2-(4-phenoxyphenyl)propanenitrile(106364-45-8)

Safety Data

• Hazardous Substances Data: 106364-45-8(Hazardous Substances Data)

Upstream product

• 124862-66-4 Acetic acid cyano-(4-phenoxy-phenyl)-methyl ester 
• 5031-78-7 4-phenoxyacetophenone 
• 4974-85-0 1-(4-phenoxyphenyl)ethyl alcohol 
• 7677-24-9 trimethylsilyl cyanide 
• 7005-72-3 4-chlorodiphenyl ether 
• 6839-20-9 2-[(methylsulfonyl)oxy]propanenitrile 

Relevant articles and documents

Asymmetric Deoxygenative Cyanation of Benzyl Alcohols Enabled by Synergistic Photoredox and Copper Catalysis?

Summary of main observation and conclusion. An enantioselective deoxygenative cyanation of benzyl alcohols was accomplished for the first time through the synergistic photoredox and copper catalysis. This reaction features the use of organic photosensitizer and low-cost 3d metal catalyst, simple and safe operations, and extremely mild conditions. A variety of chiral benzyl nitriles were produced in generally good yields and high level of enantiocontrols from readily available feedstocks (22 examples, up to 93% yield and 92% ee).

A NEW CONVENIENT SYNTHESIS OF α-ARYLPROPIONIC ACID ESTERS AND α-ARYLPROPIONITRILES

Various types of α-arylpropionic acid esters were effectively obtained by the coupling reaction of aryl Grignard reagents and α-bromopropionic acid esters in the presence of nickel catalysts. α-Arylpropionitriles, precursors of α-arylpropionic acids, were also synthesized by the reaction of α-methanesulfonyloxypropionitrile and arylcopper reagents prepared from equimolar amount of arylmagnesium halides and copper(I) bromide.