1064665-42-4

Basic information

• Product Name: γ-L-Glu-butirosin B
• Synonyms: γ-L-Glu-butirosin B
• CAS NO: 1064665-42-4
• Molecular Weight: 684.698
• Mol File: 1064665-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: γ-L-Glu-butirosin B(CAS DataBase Reference)
• NIST Chemistry Reference: γ-L-Glu-butirosin B(1064665-42-4)
• EPA Substance Registry System: γ-L-Glu-butirosin B(1064665-42-4)

Safety Data

• Hazardous Substances Data: 1064665-42-4(Hazardous Substances Data)

Upstream product

• 25546-65-0 ribostamycin 
• 1064665-41-3 γ-L-Glu-((S)-4-amino-2-hydroxybutyryl)-N-acetylcysteamine thioester 

Downstream Products

• 34291-02-6 Butirosin B 

Relevant articles and documents

Combined chemical-enzymatic assembly of aminoglycoside derivatives with N-1-AHB side chain

A series of unprotected pseudo-disaccharides and pseudo-trisaccharides of 2-deoxystreptamine-containing aminoglycosides have been selectively acylated at the N-1 position with the valuable (S)-4-amino-2-hydroxybutanoyl (AHB) pharmacophore by using the recombinant BtrH and BtrG enzymes from butirosin biosynthesis in combination with a synthetic acyl donor. The process was optimized by performing two enzymatic steps in a sequential manner without purification of the intermediate product.