1064777-59-8

Basic information

• Product Name: 3-[((1-benzyl-1H-[1,2,3]triazol-4-yl)methyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrol-2,5-dione
• Synonyms: 3-[((1-benzyl-1H-[1,2,3]triazol-4-yl)methyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrol-2,5-dione
• CAS NO: 1064777-59-8
• Molecular Weight: 528.57
• Mol File: 1064777-59-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[((1-benzyl-1H-[1,2,3]triazol-4-yl)methyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrol-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[((1-benzyl-1H-[1,2,3]triazol-4-yl)methyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrol-2,5-dione(1064777-59-8)
• EPA Substance Registry System: 3-[((1-benzyl-1H-[1,2,3]triazol-4-yl)methyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrol-2,5-dione(1064777-59-8)

Safety Data

• Hazardous Substances Data: 1064777-59-8(Hazardous Substances Data)

Upstream product

• 475473-79-1 5-methoxy-1-(prop-2-yn-1-yl)-1H-indole 
• 1064777-84-9 C₁₉H₁₈N₄O 
• 1006-94-6 5-methoxylindole 
• 879-37-8 3-indolylacetamide 
• 1064777-85-0 [1-(1-benzyl-1H-[1,2,3]triazol-4-ylmethyl)-5-methoxy-1H-indol-3-yl]-oxoacetic acid methyl ester 

Relevant articles and documents

NK CELL ACTIVATING MOLECULES, NK CELLS AND PHARMACEUTICAL COMPOSITONS COMPRISING THE SAME

The present invention relates to a compound represented by specific Formula 1; a process for preparing the same; NK cells treated with said compound; a process for treating NK cells with said compound; and a pharmaceutical composition comprising said compound or said NK cells. The present compound of Formula 1 may outstandingly increase expression of natural cytotoxicity receptors on NK cells such as NCR1, NCR2 and NCR3 and death ligands such as FasL and TRAIL. Thus, NK cel ls treated with the present compound have highly increased cytotoxicity against target cells such as cancer cells and host cells infected with viruses. Therefore, the present compound or NK cells treated with the same may be usefully used as a medical use such as anticancer agents and antiviral agents.