106535-19-7Relevant articles and documents
Mild and efficient procedure for michael addition of n-heterocycles to,-unsaturated compounds using anhydrous K3PO4 as catalyst
Hou, Xueling,Hemit, Helimay,Yong, Jianping,Nie, Lifei,Aisa, Haji Akber
, p. 973 - 979 (2010)
Imidazole, 1,2,4-triazole, indole, and benzotriazole undergo conjugate additions with,α,β-unsaturated carbonyl compounds in the presence of anhydrous potassium phosphate at ambient temperature to afford the corresponding Michael adducts in excellent yields.
Solvent- and Catalyst-Free Aza-Michael Addition of Imidazoles and Related Heterocycles
Gobec, Florian,Kodolitsch, Katharina,Slugovc, Christian
, (2020)
This work demonstrates the scope and limitations of the aza-Michael addition of imidazoles and related heterocycles with electron deficient olefins under solvent- and catalyst-free conditions. The reaction proceeds at 80 °C within hours towards completion as long as the azole derivative is sufficiently soluble in the Michael acceptor, which has been used in small excess. Workup only comprises evaporation of surplus Michael-acceptor, and no additional solvents are necessary for purifying the products.
Poly(N-vinylimidazole) as an efficient and recyclable catalyst of the aza-Michael reaction in water
Beletskaya,Tarasenko,Khokhlov,Tyurin
scheme or table, p. 461 - 467 (2010/07/06)
Poly(N-vinylimidazole) effectively catalyzed Michael addition of 1H-1,2,4-triazole, 3,5-dimethyl-1H-1,2,4-triazole, uracil, oxazolidin-2-one, and succinimide to but-3-en-2-one, cyclohex-2-en-1-one, methyl acrylate, and methyl vinyl sulfone in water at roo