106718-47-2

Basic information

• Product Name: (2-aminophenyl)cyclopentylMethanone
• Synonyms: (2-aminophenyl)cyclopentylMethanone
• CAS NO: 106718-47-2
• Molecular Weight: 189.257
• Mol File: 106718-47-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (2-aminophenyl)cyclopentylMethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-aminophenyl)cyclopentylMethanone(106718-47-2)
• EPA Substance Registry System: (2-aminophenyl)cyclopentylMethanone(106718-47-2)

Safety Data

• Hazardous Substances Data: 106718-47-2(Hazardous Substances Data)

Usage

Description

(2-aminophenyl)cyclopentylMethanone, also known as APCP, is a ketone derivative featuring a cyclopentyl ring and an aminophenyl group. It is a versatile compound in organic chemistry, commonly utilized in research and pharmaceutical applications as a building block for synthesizing various organic compounds and pharmaceutical agents. APCP possesses potential pharmacological properties and demonstrates affinity for specific receptors in the central nervous system, making it a valuable asset in drug development and neuroscience research.

Uses

Used in Pharmaceutical Research and Development:
(2-aminophenyl)cyclopentylMethanone is used as a building block for the synthesis of various organic compounds and pharmaceutical agents due to its molecular structure and reactivity.
Used in Neuroscience Research:
(2-aminophenyl)cyclopentylMethanone is used as a research tool for studying the central nervous system, given its affinity for certain receptors and potential pharmacological properties.

Upstream product

• 1885-29-6 anthranilic acid nitrile 
• 1343960-21-3 (2-aminophenyl)(cyclopentyl)methanol 
• 33240-34-5 cyclopentylmagnesium bromide 
• 32916-51-1 cyclopentylmagnesium chloride 
• 552-89-6 2-nitro-benzaldehyde 
• 529-23-7 o-aminobenzaldehyde 

Downstream Products

• 1229609-97-5 4-cyclopentyl-2-phenylquinazoline 
• 1610460-85-9 3-benzyl-3-cyclopentyl-1-methylindolin-2-one 
• 1610460-97-3 cyclopentyl(2-(methylamino)phenyl)methanone 
• 74333-57-6 (2-Azido-phenyl)-cyclopentyl-methanone 
• 942231-93-8 C₃₅H₃₈N₄O₅ 
• 528882-28-2 3-(2-(5-cyclopentyl-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-1,2-dihydro-3H-1,3,4-benzotriazepin-3-yl)-acetylamino)-benzoic acid 
• 942231-86-9 C₁₆H₂₃N₃O₂ 

Relevant articles and documents

A novel and efficient methodology for the construction of quinazolines based on supported copper oxide nanoparticles

A series of quinazolines were synthesized from 2-aminobenzophenones and benzylic amines in good to excellent yields by employing a new heterogeneous catalyst based on the copper oxide nanoparticles supported on kaolin.

Gold-catalyzed cyclization of 1-(2′-Azidoaryl) propynols: Synthesis of polysubstituted 4-quinolones

An unprecedented gold-catalyzed procedure for the synthesis of polysubstituted 4-quinolones from 1-(2′-Azidoaryl) propynols is described. The reaction undergoes an intramolecular nucleophilic attack of the azide group to the Au-Activated triple bonds in a 6-endo-dig manner and subsequent gold-Assisted expulsion of N2 to furnish an α-imino gold carbene intermediate, which triggers a 1,2-carbon migration and finally is converted to 2,3-disubstituted 4-quinolone.

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.