106757-55-5

Basic information

• Product Name: R-METHYL 3-(2,2-DIMETHYL 1,3-DIOXOLANE-4-YL)-TRANS-2-PROPENOATE
• Synonyms: R-METHYL 3-(2,2-DIMETHYL 1,3-DIOXOLANE-4-YL)-TRANS-2-PROPENOATE
• CAS NO: 106757-55-5
• Molecular Formula: C₉H₁₄O₄
• Molecular Weight: 186.21
• Mol File: 106757-55-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 260.961°C at 760 mmHg
• Flash Point: 95.556°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: R-METHYL 3-(2,2-DIMETHYL 1,3-DIOXOLANE-4-YL)-TRANS-2-PROPENOATE(CAS DataBase Reference)
• NIST Chemistry Reference: R-METHYL 3-(2,2-DIMETHYL 1,3-DIOXOLANE-4-YL)-TRANS-2-PROPENOATE(106757-55-5)
• EPA Substance Registry System: R-METHYL 3-(2,2-DIMETHYL 1,3-DIOXOLANE-4-YL)-TRANS-2-PROPENOATE(106757-55-5)

Safety Data

• Hazardous Substances Data: 106757-55-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H14O4/c1-9(2)12-6-7(13-9)4-5-8(10)11-3/h4-5,7H,6H2,1-3H3/b5-4+/t7-/m1/s1

Upstream product

• 1779-58-4 (methyloxycarbonylmethyl)triphenylphosphonium bromide 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 91274-05-4 (2S,3S)-1,2-O-isopropylidene-1,2,3,4-tetrol 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 97776-79-9 4,5-O-isopropylidene-L-arabinose dibenzyl thioacetal 
• 56710-46-4 L-5,6-isopropylidene-gulono-1,4-lactone 
• 116-11-0 2-Methoxypropene 
• 1128-23-0 L-gulono-1,4-lactone 
• 5927-18-4 trimethyl phosphonoacetate 

Downstream Products

• 119814-58-3 (R)-4-((E)-3-Benzenesulfonylmethoxy-propenyl)-2,2-dimethyl-[1,3]dioxolane 
• 122410-16-6 (R)-2,2-Dimethyl-4-((E)-3-phenylsulfanylmethoxy-propenyl)-[1,3]dioxolane 
• 934503-38-5 5-{7-[(1R,2S)-2-((17S,18S)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptane-1-sulfonyl}-1-phenyl-1H-tetrazole 
• 934503-06-7 5-{7-[(1R,2S)-2-((17S,18S)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole 
• 934502-97-3 5-((16S,17S)-16-methoxy-17-methylpentatriacontane-1-sulfonyl)-1-phenyl-1H-triazole 
• 934503-48-7 5-((16S,17S)-16-methoxy-17-methylpentatriacontyl-1-sulfanyl)-1-phenyl-1H-tetrazole 
• 847800-67-3 (R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-(dimethyl-phenyl-silanyl)-propionic acid methyl ester 
• 847800-66-2 (S)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-(dimethyl-phenyl-silanyl)-propionic acid methyl ester 
• 106757-57-7 (R,E)-3-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)prop-2-en-1-ol 

Relevant articles and documents

A pyrrolysine analogue for protein click chemistry

(Chemical Equation Presented) Ignoring the STOP sign: A pyrrolysine analogue bearing a terminal alkyne was site-specifically incorporated into recombinant calmodulin (CaM) through a UAG codon. The resulting protein was labeled with an azide-containing dye using a copper(I)-catalyzed click reaction. Subsequent application of an orthogonal cysteine tagging method yielded a CaM labeled with two distinct fluorophores that enabled its study by FRET spectroscopy.

Synthesis of key fragments of amphidinolide Q - A cytotoxic 12-membered macrolide

β-Hydroxy aldehyde and alkyl ketone moieties were effectively synthesized as key intermediates of amphidinolide Q, a cytotoxic macrolide from the cultured dinoflagellate Amphidinium sp.. The asymmetric center of the former derivative was produced by Sharpless asymmetric epoxidation, followed by E-selective 1,4-addition to give the sp2 methyl group. Derivatization of the L-ascorbic acid derivative by Evans asymmetric alkylation and Peterson olefination provided the latter intermediate. The coupling reaction of the segments was examined.

The first syntheses of single enantiomers of the major methoxymycolic acid of Mycobacterium tuberculosis

The synthesis of three stereoisomers of a major homologue of the methoxymycolic acids present in Mycobacterium tuberculosis is described.