106860-17-7 Usage
Description
(2S)-2-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride is a chemical compound with the molecular formula C11H14ClNO2. It is a derivative of L-Homophenylalanine, an antitumor agent, and is used as an intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
(2S)-2-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride is used as an intermediate in the synthesis of L-Homophenylalanine, which is an antitumor agent. It plays a crucial role in the development of pharmaceutical compounds that target cancer cells and help in the treatment of various types of cancer.
Used in Drug Synthesis:
(2S)-2-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride is used as a key component in the synthesis of various drug molecules. Its unique chemical structure allows it to form stable bonds with other molecules, making it an essential building block in the creation of new and effective pharmaceutical compounds.
Used in Research and Development:
(2S)-2-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride is also used in research and development for the discovery of new drug candidates and the optimization of existing ones. Its versatile chemical properties make it a valuable tool for scientists working in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 106860-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,8,6 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106860-17:
(8*1)+(7*0)+(6*6)+(5*8)+(4*6)+(3*0)+(2*1)+(1*7)=117
117 % 10 = 7
So 106860-17-7 is a valid CAS Registry Number.
106860-17-7Relevant articles and documents
Chiral Pyridoxal-Catalyzed Asymmetric Biomimetic Transamination of α-Keto Acids
Shi, Limin,Tao, Chuangan,Yang, Qin,Liu, Yong Ethan,Chen, Jing,Chen, Jianfeng,Tian, Jiaxin,Liu, Feng,Li, Bo,Du, Yongling,Zhao, Baoguo
, p. 5784 - 5787 (2015/12/11)
A series of chiral pyridoxals 8 and 9 have been developed from commercially available pyridoxine and (S)-α,α-diarylprolinols. The pyridoxals exhibited good catalytic activity in an asymmetric transamination of α-keto acids with 2,2-diphenylglycine (7f) as the amine source to give various α-amino acids in 29-85% yields with 53-80% ee's. The current asymmetric transamination has successfully mimicked a complete biological transamination process characterized by two half-transaminations, a small chiral pyridoxal molecule acting as the catalyst, and enantioselective control.
N-benzoyl amino acids as LFA-1/ICAM inhibitors 1: Amino acid structure-activity relationship
Burdick, Daniel J.,Paris, Ken,Weese, Kenneth,Stanley, Mark,Beresini, Maureen,Clark, Kevin,McDowell, Robert S.,Marsters Jr., James C.,Gadek, Thomas R.
, p. 1015 - 1018 (2007/10/03)
The association of ICAM-1 with LFA-1 plays a critical role in several autoimmune diseases. N-2-Bromobenzoyl L-tryptophan, compound 1, was identified as an inhibitor to the formation of the LFA-1/ICAM complex. The SAR of the amino acid indicates that the carboxylic acid is required for inhibition and that L-histidine is the most favored amino acid.
