106918-31-4

Basic information

• Product Name: 1-methoxy-2-(4-carbomethoxyphenyl)ethylene
• Synonyms: 1-methoxy-2-(4-carbomethoxyphenyl)ethylene
• CAS NO: 106918-31-4
• Molecular Weight: 192.214
• Mol File: 106918-31-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-methoxy-2-(4-carbomethoxyphenyl)ethylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-2-(4-carbomethoxyphenyl)ethylene(106918-31-4)
• EPA Substance Registry System: 1-methoxy-2-(4-carbomethoxyphenyl)ethylene(106918-31-4)

Safety Data

• Hazardous Substances Data: 106918-31-4(Hazardous Substances Data)

Upstream product

• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 22744-12-3 [4-(methoxycarbonyl)phenyl]acetic acid 
• 46190-45-8 4-(2-hydroxyethyl)benzoic acid methyl ester 
• 1416069-73-2 (4-(2,2-dimethoxyethyl)phenyl)methanol 
• 47019-30-7 methyl (E)-4-(4-methylstyryl)benzoate 
• 1361229-76-6 4-[2-(4-methoxybenzamido)thiazol-5-yl]benzoic acid 
• 47019-31-8 (Z)-methyl 4-(4-methylstyryl)benzoate 
• 119770-58-0 (6S)-11-deazatetrahydrohomofolate 
• 119787-36-9 (6R,S)-11-deaza-10-methyltetrahydrohomofolate 
• 119770-55-7 11-deaza-10-methylhomofolic acid 
• 119770-57-9 11-deaza-10-methyl-7,8-dihydrohomofolate 
• 119770-56-8 11-deaza-7,8-dihydrohomofolate 
• 119770-54-6 11-deazahomofolic acid 
• 119770-50-2 1-<(2-amino-4-hydroxy-5-nitropyrimidin-6-yl)amino>-5-(p-carbomethoxyphenyl)-4-methyl-2-pentanone oxime 
• 119770-49-9 1-<(2-amino-4-hydroxy-5-nitropyrimidin-6-yl)amino>-5-(p-carbomethoxyphenyl)-2-pentanone oxime 

Relevant articles and documents

Folate analogues. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferase

The Boon-Leigh procedure, involving condensation of a 6-chloro-5-nitropyrimidine (22) with an α-amino ketone (20 or 21) followed by reduction of the nitro group, cyclization, and L-glutamylation, led to the formation of 11-deazahomofolate (29) and its 10-

Reductive N-Arylethylation of Aromatic Amines and N-Heterocycles with Enol Ethers

A convenient method for N-arylethylation of aromatic amines and heterocycles under mild reductive conditions was developed using (2-methoxyvinyl)(hetero)arenes as building blocks and triethylsilane/trifluoroacetic acid as reducing agent. This protocol is compatible with numerous functional groups, and aliphatic amines are inert due to protonation.

Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds

Protein kinase CK2 (CK2) is a ubiquitous serine/threonine protein kinase for hundreds of endogenous substrates. CK2 has been considered to be involved in many diseases, including cancers. Herein we report the discovery of a novel ATP-competitive CK2 inhibitor. Virtual screening of a compound library led to the identification of a hit 2-phenyl-1,3,4-thiadiazole compound. Subsequent structural optimization resulted in the identification of a promising 4-(thiazol-5-yl)benzoic acid derivative.