107096-57-1Relevant articles and documents
Reductive heterocyclizations via indium-iodine-promoted conversion of 2-nitroaryl imines or 2-nitroarenes to 2,3-diaryl-substituted indazoles
Ahn, Gil Hwan,Lee, Jung June,Jun, Young Moo,Lee, Byung Min,Kim, Byeong Hyo
, p. 2472 - 2485 (2007)
While N-(2-nitrobenzylidene)anilines produced mixtures of 2,1-benzisoxazoles and 3-anilino-2-aryl-2H-indazoles in the presence of indium and iodine in MeOH, N-(2-nitrobenzylidene)anilines were transformed into 3-anilino-2-aryl-2H-indazoles as the predominant major product through the change of the solvent from protic MeOH to aprotic THF. In an indium-mediated one-pot reductive reaction, 2-benzaldehydes and anilines in THF were also successfully transformed into the corresponding indazoles. This journal is The Royal Society of Chemistry.
THE CYCLISATION AND REARRANGEMENT OF THE NITRO DERIVATIVES OF AROMATIC HYDROCARBONS IN TRIFLUOROMETHANESULPHONIC ACID
Bullen, John V.,Ridd, John H.,Sabek, Omaima
, p. 291 - 296 (2007/10/02)
A number of the nitro derivatives of aromatic hydrocarbons undergo reactions in trifluoromethanesulphonic acid at ca. 100 deg C in which either the nitro group undergoes a 1,3-rearrangement or cyclisation occurs to form an anthranil.The rates and product composition have been determined for reactions in which the subsituents ortho to the nitro group are methyl or ethyl.For the rearrangement reaction to occur, it appears necessary that the nitro group should be initially between two alkyl substituents.The cyclisation reaction is significant only when one of the ortho-substituents is an ethyl group.