107114-97-6

Basic information

• Product Name: Methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-dithiocarbamic acid methyl ester
• Synonyms: Methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-dithiocarbamic acid methyl ester
• CAS NO: 107114-97-6
• Molecular Weight: 349.425
• Mol File: 107114-97-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-dithiocarbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-dithiocarbamic acid methyl ester(107114-97-6)
• EPA Substance Registry System: Methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-dithiocarbamic acid methyl ester(107114-97-6)

Safety Data

• Hazardous Substances Data: 107114-97-6(Hazardous Substances Data)

Upstream product

• 107114-94-3 3-cyano-2,3-dihydro-2-(methylimino)-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole 
• 107114-95-4 2-(methylcyanamido)-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole 
• 107114-93-2 2-(methylamino)-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole 
• 107115-00-4 2-chloro-5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole 
• 74-88-4 methyl iodide 

Downstream Products

• 96-45-7 N,N'-ethylenethiourea 
• 107114-93-2 2-(methylamino)-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole 
• 107114-90-9 (4,5-Dihydro-1H-imidazol-2-yl)-methyl-[5-(2-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-amine 

Relevant articles and documents

Substituted 1,3,4-Thiadiazoles with Anticonvulsant Activity. 3. Guanidines

The synthesis and anticonvulsant activity of a number of 2-aryl-5-guanidino-1,3,4 thiadiazoles are described.The unsubstituted guanidine 2a was found to possess potent anticonvulsant properties; considerable reduction or loss of activity however was observed with the majority of the substituted guanidines.Incorporation of the guanidine group into an imidazoline ring also resulted in a loss of activity.Secondary pharmacological evaluation confirmed the anticonvulsant properties of 2a but also revelated that the compound exibited a considerable degree of sedative activity.