1071506-72-3

Basic information

• Product Name: 5-amino-3-allylcarbamoyl-2,4,6-triiodobenzoyl chloride
• Synonyms: 5-amino-3-allylcarbamoyl-2,4,6-triiodobenzoyl chloride
• CAS NO: 1071506-72-3
• Molecular Weight: 616.363
• Mol File: 1071506-72-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-amino-3-allylcarbamoyl-2,4,6-triiodobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-3-allylcarbamoyl-2,4,6-triiodobenzoyl chloride(1071506-72-3)
• EPA Substance Registry System: 5-amino-3-allylcarbamoyl-2,4,6-triiodobenzoyl chloride(1071506-72-3)

Safety Data

• Hazardous Substances Data: 1071506-72-3(Hazardous Substances Data)

Upstream product

• 107-11-9 1-amino-2-propene 
• 37441-29-5 5-amino-2,4,6-triiodoisophthalic acid dichloride 

Downstream Products

• 946506-14-5 acetic acid [3-(allylcarbamoyl)-5-chlorocarbonyl-2,4,6-triiodo-phenylcarbamoyl]-methyl ester 
• 946506-20-3 acetic acid 2,3-diacetoxy-1-(3-allylcarbamoyl-5-chlorocarbonyl-2,4,6-triiodo-phenylcarbamoyl)-propyl ester 
• 946506-17-8 acetic acid 2-acetoxy-2-(3-allylcarbamoyl-5-chlorocarbonyl-2,4,6-triiodo-phenylcarbamoyl)-ethyl ester 
• 73334-07-3 iopromide 

Relevant articles and documents

The new method of preparing [...]

The present invention relates to iopromide preparation methods, and provides three new iopromide preparation methods, wherein the method 1 comprises that a compound represented by a formula II is adopted as a starting raw material and reacts with allylamine to obtain a compound represented by a formula III, the compound represented by the formula III reacts with N-methyl allylamine to obtain a compound represented by a formula IV, the compound represented by the formula IV reacts with methoxyacetyl chloride to obtain a compound represented by a formula V, and the compound represented by the formula V is oxidized to obtain the iopromide represented by a formula I, the method 2 comprises that the compound represented by the formula II is adopted as a starting raw material and reacts with allylamine to obtain the compound represented by the formula III, the compound represented by the formula III reacts with methoxyacetyl chloride to obtain a compound represented by a formula IV-1, the compound represented by the formula IV-1 reacts with N-methyl allylamine to obtain the compound represented by the formula V, and the compound represented by the formula V is oxidized to obtain the iopromide represented by the formula I, the method 3 comprises that the compound represented by the formula II is adopted as a starting raw material and reacts with allylamine to obtain the compound represented by the formula III, the compound represented by the formula III reacts with methoxyacetyl chloride to obtain the compound represented by the formula IV-1, the compound represented by the formula IV-1 reacts with 3-methylamino-1,2-propanediol to obtain a compound represented by a formula V-1, and the compound represented by the formula V-1 is oxidized to obtain the iopromide represented by the formula I, and the method 4 comprises that the compound represented by the formula II is adopted as a starting raw material and reacts with methoxyacetyl chloride obtain a compound represented by a formula III-1, the compound represented by the formula III-1 reacts with allylamine to obtain the compound represented by the formula IV-1, the compound represented by the formula IV-1 reacts with N-methyl allylamine to obtain the compound represented by the formula V, and the compound represented by the formula V is oxidized to obtain the iopromide represented by the formula I.

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic N-heterocyclic central moiety such as pyrrolidine or piperidine heterocycles allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging, in particular in X-ray imaging, and to contrast media containing such compounds.