107254-86-4 Usage
Description
NPPB, also known as 5-Nitro-2-(3-phenylpropylamino) benzoic acid, is a chemical compound that serves as a potent and selective inhibitor of the anion exchanger AE1. It is widely used in various applications due to its unique properties and functions.
Uses
Used in Biochemical Applications:
NPPB is used as a Clchannel blocker for studying the role of chloride channels in various biological processes. Its ability to inhibit these channels helps researchers understand their function and potential therapeutic applications.
Used in Pharmaceutical Applications:
NPPB is used as a GPR35 agonist, which is a G-protein coupled receptor involved in various physiological processes. Activation of GPR35 by NPPB can lead to the modulation of immune responses and has potential implications in the treatment of certain diseases.
Used in Cellular Respiration Studies:
NPPB is used to uncouple mitochondrial ATP synthesis in phagocytes, as it maintains protonophoric activity. This property allows researchers to study the effects of uncoupling on cellular respiration and energy production in cells.
Biological Activity
Very potent chloride channel blocker.
Biochem/physiol Actions
Potent chloride channel blocker.
Check Digit Verification of cas no
The CAS Registry Mumber 107254-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,2,5 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 107254-86:
(8*1)+(7*0)+(6*7)+(5*2)+(4*5)+(3*4)+(2*8)+(1*6)=114
114 % 10 = 4
So 107254-86-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
