1072833-70-5

Basic information

• Product Name: [(1R)-1-({[(2-bromobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid
• Synonyms: [(1R)-1-({[(2-bromobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid
• CAS NO: 1072833-70-5
• Molecular Weight: 371.039
• Mol File: 1072833-70-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [(1R)-1-({[(2-bromobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [(1R)-1-({[(2-bromobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid(1072833-70-5)
• EPA Substance Registry System: [(1R)-1-({[(2-bromobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid(1072833-70-5)

Safety Data

• Hazardous Substances Data: 1072833-70-5(Hazardous Substances Data)

Upstream product

• 1310383-72-2 (1R)-3-methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborole-2-yl]butan-1-amine trifluoroacetatic acid salt 
• 847494-22-8 2-amino-N-{(1R)-3-methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborol-2-yl]butyl}acetamide monohydrochloride 
• 847494-18-2 tert-butyl [2-({(1R)-3-methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethyl hexahydro-4,6-methano-1,3,2-benzodioxaborole-2-yl]butyl}amino)-2-oxoethyl]carbamate 
• 1310383-72-2 (aR,3aS,4S,6S,7aR)-hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate 
• 1072833-91-0 2-bromo-N-[2-({(1R)-3-methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethyl hexahydro-4,6-methano-1,3,2-benzodioxaborole-2-yl]butyl}amino)2-oxoethyl]benzamide 
• 84110-40-7 Dihydroxy-isobutyl-boran 

Relevant articles and documents

PROTEASOME INHIBITOR

PROBLEM TO BE SOLVED: To provide a novel compound useful as a proteasome inhibitor. SOLUTION: The invention also provides a pharmaceutical composition comprising the compound, and a method of using the composition for treatment of various diseases. The compound is a compound of the general formula (I) or a pharmaceutical acceptable salt or boronic acid anhydride thereof. In the formula, Z1 and Z2 are each independently hydroxy, alkoxy, aryloxy or aralkoxy, or Z1 and Z2 together form a moiety derived from a boronic acid complexing agent. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Proteasome inhibitor composition and use thereof (by machine translation)

This application relates to proteasome inhibitor and its composition and use. The present invention provides a novel compound of a proteasome inhibitor. The invention also provides containing the compounds of the invention, a pharmaceutical composition of composition and the method for the treatment of various diseases. (by machine translation)

PROTEASOME INHIBITORS

The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.