1072880-18-2Relevant articles and documents
Synthesis of new indeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-diones as potential antitumor agents
Insuasty, Braulio,Orozco, Fabian,Lizarazo, Carolina,Quiroga, Jairo,Abonia, Rodrigo,Hursthouse, Mike,Nogueras, Manuel,Cobo, Justo
, p. 8492 - 8500 (2008/12/23)
Novel racemic indeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-diones 3-29 were obtained regioselectivily from the reaction of 5,6-diamino-3,4-dihydropyrimidin-4-ones 1 and 2-arylideneindandiones 2 as reagents. These compounds have been evaluated at the US